Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695, USA.
Chem Commun (Camb). 2014 Dec 11;50(95):15105-8. doi: 10.1039/c4cc07004f.
Self-folded redox/acid dual-responsive nanocarriers (RAD-NCs) are developed for physiologically triggered delivery of anticancer drugs. The evidenced redox/acid responsiveness, facile decoration of ligands, and active tumor-targeting capability of RAD-NCs suggest their potential as a promising formulation for tumor-targeted chemotherapy.
自折叠氧化还原/酸双重响应纳米载体（RAD-NCs）被开发用于生理触发的抗癌药物递送。RAD-NCs 的氧化还原/酸响应性、配体的易于修饰和主动肿瘤靶向能力的证据表明，它们有可能成为肿瘤靶向化疗的一种有前途的制剂。
