自我复原力的发展：与幼儿期观察到的养育方式及血清素转运体基因多态性的关系
Development of Ego-Resiliency: Relations to Observed Parenting and Polymorphisms in the Serotonin Transporter Gene During Early Childhood.
作者信息
Taylor Zoe E, Sulik Michael J, Eisenberg Nancy, Spinrad Tracy L, Silva Kassondra M, Lemery-Chalfant Kathryn, Stover Daryn A, Verrelli Brian C
机构信息
Department of Psychology, Arizona State University.
School of Social and Family Dynamics, Arizona State University.
出版信息
Soc Dev. 2014 Aug 1;23(3):433-450. doi: 10.1111/sode.12041.
Abstract
We used observed parenting behaviors, along with genetic variants and haplotypes of the serotonin transporter gene (SLC6A4), as predictors of children's ego-resiliency during early childhood ( =153). Quality of mothers' parenting was observed at 18 months of age and mothers' reports of ego-resiliency were collected at six time points from 18 to 84 months. Genetic data were collected at 72 months. Observed parenting was positively associated with initial levels of children's ego-resiliency. Furthermore, although individual genetic variants of the serotonin transporter gene (LPR, STin2) were not associated with ego-resiliency, the S10 haplotype (that combines information from these two variants) was negatively associated with initial levels of ego-resiliency. Both parenting and serotonin genetic variation uniquely predicted children's ego-resiliency, suggesting an additive effect of genetic and parental factors.
摘要
我们将观察到的育儿行为，以及血清素转运体基因（SLC6A4）的基因变异和单倍型，作为幼儿期儿童自我恢复力的预测指标（n = 153）。在18个月大时观察母亲的育儿质量，并在18至84个月的六个时间点收集母亲关于自我恢复力的报告。在72个月时收集基因数据。观察到的育儿行为与儿童自我恢复力的初始水平呈正相关。此外，虽然血清素转运体基因的个体基因变异（LPR、STin2）与自我恢复力无关，但S10单倍型（结合了这两个变异的信息）与自我恢复力的初始水平呈负相关。育儿行为和血清素基因变异都能独特地预测儿童的自我恢复力，这表明基因因素和父母因素具有累加效应。
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