Goh C L
Contact Clinic, Middle Road Hospital, Singapore.
Br J Dermatol. 1989 Jan;120(1):77-82. doi: 10.1111/j.1365-2133.1989.tb07768.x.
Thirty-four per cent of 2110 patients with eczema attending a contact dermatitis clinic had hand eczema. Fifty-five per cent (395 of 721) had contact dermatitis and 45% (326 of 721) had endogenous/unclassifiable eczema. Thirty-five per cent of cases (217 of 721) were occupational eczema. An epidemiological comparison of patients with occupational and non-occupational hand eczema (defined as eczema occurring on the hands up to the wrist line) was made. Hand eczema was more common in males in both groups, and there was a significantly larger proportion of males in the occupational group (65%) than the non-occupational group (51%) (P less than 0.001). The prevalence of a personal or family history of atopy was significantly lower in the occupational group (7%) than the non-occupational group (15%) (P less than 0.005). Irritant contact dermatitis occurred in a larger proportion of patients in the occupational group (76%) than the non-occupational group (39%) (P less than 0.0001). There was no significant difference between the proportions of patients with positive patch test reactions in the occupational group (34%) and the non-occupational group (41%). Potassium dichromate, and epoxy resin allergy occurred significantly, more frequently, in the occupational group whereas fragrance-mix allergy was significantly more frequent in the non-occupational group.
在一家接触性皮炎诊所就诊的2110例湿疹患者中，34%患有手部湿疹。721例患者中，55%（395例）患有接触性皮炎，45%（326例）患有内源性/无法分类的湿疹。721例病例中，35%（217例）为职业性湿疹。对职业性和非职业性手部湿疹患者（定义为手部至腕部出现的湿疹）进行了流行病学比较。两组中手部湿疹在男性中更为常见，职业组男性比例（65%）显著高于非职业组（51%）（P<0.001）。职业组中个人或家族过敏史的患病率（7%）显著低于非职业组（15%）（P<0.005）。职业组中刺激性接触性皮炎患者的比例（76%）高于非职业组（39%）（P<0.0001）。职业组（34%）和非职业组（41%）中斑贴试验阳性反应患者的比例无显著差异。职业组中重铬酸钾和环氧树脂过敏的发生率显著更高，而非职业组中香料混合物过敏的发生率显著更高。
