Creemers-Schild D, Gronthoud F, Spanjaard L, Visser L G, Brouwer C N M, Kuijper E J
Department of Infectious Diseases, Leiden University Medical Center Leiden, the Netherlands.
Department of Medical Microbiology, Academic Medical Center Amsterdam, the Netherlands.
New Microbes New Infect. 2014 May;2(3):52-7. doi: 10.1002/nmi2.39. Epub 2014 Mar 25.
Fusobacterium necrophorum is a rare causative agent of otitis and sinusitis. Most commonly known is the classic Lemièrre's syndrome of postanginal sepsis with suppurative thrombophlebitis of the jugular vein. We report five patients diagnosed recently with a complicated infection with F. necrophorum originating from otitis or sinusitis. Two patients recovered completely, one patient died due to complications of the infection, one patient retained a slight hemiparesis and one patient had permanent hearing loss. Diagnosis and management are discussed. A possible factor in the emergence of F. necrophorum is proposed.
坏死梭杆菌是中耳炎和鼻窦炎的罕见病原体。最广为人知的是经典的 Lemierre 综合征,即咽后败血症合并颈静脉化脓性血栓性静脉炎。我们报告了最近诊断出的 5 例由坏死梭杆菌引起的复杂感染患者,感染源为中耳炎或鼻窦炎。2 例患者完全康复,1 例患者因感染并发症死亡,1 例患者遗留轻度偏瘫,1 例患者有永久性听力损失。本文讨论了诊断和治疗方法。并提出了坏死梭杆菌出现的一个可能因素。