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SketchBio:一款科学家用于分子建模和动画的 3D 界面。

SketchBio: a scientist's 3D interface for molecular modeling and animation.

机构信息

University of North Carolina at Chapel Hill, 27599 Chapel Hill, NC, USA.

出版信息

BMC Bioinformatics. 2014 Oct 30;15(1):334. doi: 10.1186/1471-2105-15-334.

DOI:10.1186/1471-2105-15-334
PMID:25359079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4287593/
Abstract

BACKGROUND

Because of the difficulties involved in learning and using 3D modeling and rendering software, many scientists hire programmers or animators to create models and animations. This both slows the discovery process and provides opportunities for miscommunication. Working with multiple collaborators, a tool was developed (based on a set of design goals) to enable them to directly construct models and animations.

RESULTS

SketchBio is presented, a tool that incorporates state-of-the-art bimanual interaction and drop shadows to enable rapid construction of molecular structures and animations. It includes three novel features: crystal-by-example, pose-mode physics, and spring-based layout that accelerate operations common in the formation of molecular models. Design decisions and their consequences are presented, including cases where iterative design was required to produce effective approaches.

CONCLUSIONS

The design decisions, novel features, and inclusion of state-of-the-art techniques enabled SketchBio to meet all of its design goals. These features and decisions can be incorporated into existing and new tools to improve their effectiveness.

摘要

背景

由于学习和使用 3D 建模和渲染软件存在困难,许多科学家聘请程序员或动画师来创建模型和动画。这既减缓了发现过程,又为错误沟通提供了机会。在与多个合作者合作的过程中,开发了一种工具(基于一系列设计目标),使他们能够直接构建模型和动画。

结果

介绍了 SketchBio,这是一种工具,它结合了最新的双手交互和阴影效果,能够快速构建分子结构和动画。它包括三个新颖的功能:示例晶体、姿势模式物理和基于弹簧的布局,这些功能加速了常见的分子模型形成操作。介绍了设计决策及其后果,包括需要迭代设计才能产生有效方法的情况。

结论

设计决策、新颖的功能和最新技术的应用使 SketchBio 能够满足其所有设计目标。这些功能和决策可以被整合到现有的和新的工具中,以提高它们的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/766391086fd6/12859_2014_6696_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/42bff366bb05/12859_2014_6696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/383eed627f2c/12859_2014_6696_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/4127cf7b5259/12859_2014_6696_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/c1f57aa070b9/12859_2014_6696_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/e99fd3463f52/12859_2014_6696_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/f9a96e1465e6/12859_2014_6696_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/d5c9bec7c385/12859_2014_6696_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/990a6930ff44/12859_2014_6696_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/c889ec227d01/12859_2014_6696_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/d3eb86278199/12859_2014_6696_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/766391086fd6/12859_2014_6696_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/42bff366bb05/12859_2014_6696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/383eed627f2c/12859_2014_6696_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/4127cf7b5259/12859_2014_6696_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/c1f57aa070b9/12859_2014_6696_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/e99fd3463f52/12859_2014_6696_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/f9a96e1465e6/12859_2014_6696_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/d5c9bec7c385/12859_2014_6696_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/990a6930ff44/12859_2014_6696_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/c889ec227d01/12859_2014_6696_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/d3eb86278199/12859_2014_6696_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0276/4287593/766391086fd6/12859_2014_6696_Fig11_HTML.jpg

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