• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy.利用二次谐波偏振显微镜对非小细胞肺癌中的胶原蛋白进行表征
Biomed Opt Express. 2014 Sep 11;5(10):3562-7. doi: 10.1364/BOE.5.003562. eCollection 2014 Oct 1.
2
Ultrastructural features of collagen in thyroid carcinoma tissue observed by polarization second harmonic generation microscopy.通过偏振二次谐波产生显微镜观察甲状腺癌组织中胶原蛋白的超微结构特征。
Biomed Opt Express. 2015 Aug 21;6(9):3475-81. doi: 10.1364/BOE.6.003475. eCollection 2015 Sep 1.
3
Changes of collagen ultrastructure in breast cancer tissue determined by second-harmonic generation double Stokes-Mueller polarimetric microscopy.利用二次谐波产生双斯托克斯-穆勒偏振显微镜测定乳腺癌组织中胶原超微结构的变化。
Biomed Opt Express. 2016 Sep 15;7(10):4054-4068. doi: 10.1364/BOE.7.004054. eCollection 2016 Oct 1.
4
Polarimetric second-harmonic generation microscopy of the hierarchical structure of collagen in stage I-III non-small cell lung carcinoma.I-III期非小细胞肺癌中胶原蛋白层次结构的偏振二次谐波生成显微镜检查
Biomed Opt Express. 2020 Mar 9;11(4):1851-1863. doi: 10.1364/BOE.387744. eCollection 2020 Apr 1.
5
Improved quantification of collagen anisotropy with polarization-resolved second harmonic generation microscopy.利用偏振分辨二次谐波产生显微镜改进胶原蛋白各向异性的定量分析。
J Biophotonics. 2017 Sep;10(9):1171-1179. doi: 10.1002/jbio.201600197. Epub 2016 Oct 24.
6
Motion-artifact-robust, polarization-resolved second-harmonic-generation microscopy based on rapid polarization switching with electro-optic Pockells cell and its application to in vivo visualization of collagen fiber orientation in human facial skin.基于电光普克尔盒快速偏振切换的运动伪像稳健、偏振分辨二次谐波产生显微镜及其在人体面部皮肤胶原纤维取向体内可视化中的应用
Biomed Opt Express. 2014 Mar 7;5(4):1099-113. doi: 10.1364/BOE.5.001099. eCollection 2014 Apr 1.
7
In vivo structural imaging of the cornea by polarization-resolved second harmonic microscopy.通过偏振分辨二次谐波显微镜对角膜进行体内结构成像。
Biomed Opt Express. 2012 Jan 1;3(1):1-15. doi: 10.1364/BOE.3.000001. Epub 2011 Dec 1.
8
Monte Carlo simulation of polarization-sensitive second-harmonic generation and propagation in biological tissue.生物组织中偏振敏感二次谐波产生与传播的蒙特卡罗模拟
J Biophotonics. 2018 Dec;11(12):e201800036. doi: 10.1002/jbio.201800036. Epub 2018 Jul 31.
9
Polarization-dependent second-harmonic generation for collagen-based differentiation of breast cancer samples.基于偏振相关性二次谐波产生的乳腺癌样本胶原差异分化
J Biophotonics. 2020 Oct;13(10):e202000180. doi: 10.1002/jbio.202000180. Epub 2020 Aug 12.
10
Pixel-level angular quantification of capsular collagen in second harmonic generation microscopy images of encapsulated thyroid nodules.对包裹性甲状腺结节的二次谐波显微镜图像中的囊壁胶原进行像素级角量化。
J Biophotonics. 2020 Dec;13(12):e202000262. doi: 10.1002/jbio.202000262. Epub 2020 Sep 18.

引用本文的文献

1
Double Stokes polarimetric microscopy for chiral fibrillar aggregates.用于手性纤维状聚集体的双斯托克斯偏振显微镜。
Sci Rep. 2025 Feb 6;15(1):4464. doi: 10.1038/s41598-025-86893-0.
2
Characterization of pathological stomach tissue using polarization-sensitive second harmonic generation microscopy.使用偏振敏感二次谐波产生显微镜对病理性胃组织进行表征。
Biomed Opt Express. 2023 Sep 22;14(10):5376-5391. doi: 10.1364/BOE.500335. eCollection 2023 Oct 1.
3
Polarimetric second harmonic generation microscopy of partially oriented fibers II: Imaging study.偏光二次谐波产生显微镜对部分取向纤维的研究 II:成像研究。
Biophys J. 2023 Oct 3;122(19):3937-3949. doi: 10.1016/j.bpj.2023.08.015. Epub 2023 Aug 23.
4
Polarimetric second-harmonic generation microscopy of partially oriented fibers I: Digital modeling.偏光二次谐波产生显微镜对部分取向纤维的研究 I:数字建模。
Biophys J. 2023 Oct 3;122(19):3924-3936. doi: 10.1016/j.bpj.2023.08.016. Epub 2023 Aug 22.
5
Unsupervised determination of lung tumor margin with widefield polarimetric second-harmonic generation microscopy.利用广角偏振二次谐波产生显微镜对肺肿瘤边缘进行无监督确定。
Sci Rep. 2022 Dec 1;12(1):20713. doi: 10.1038/s41598-022-24973-1.
6
PSHG-TISS: A collection of polarization-resolved second harmonic generation microscopy images of fixed tissues.PSHG-TISS:一组固定组织的偏振分辨二次谐波产生显微镜图像集合。
Sci Data. 2022 Jul 2;9(1):376. doi: 10.1038/s41597-022-01477-1.
7
Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy.基于宽场偏振二次谐波显微镜的机器学习癌症诊断
Sci Rep. 2022 Jun 18;12(1):10290. doi: 10.1038/s41598-022-13623-1.
8
Navigating the Collagen Jungle: The Biomedical Potential of Fiber Organization in Cancer.探索胶原蛋白丛林:癌症中纤维组织的生物医学潜力
Bioengineering (Basel). 2021 Jan 21;8(2):17. doi: 10.3390/bioengineering8020017.
9
Characterization of pathological thyroid tissue using polarization-sensitive second harmonic generation microscopy.应用偏振敏感二次谐波产生显微镜对病态甲状腺组织进行特征分析。
Lab Invest. 2020 Oct;100(10):1280-1287. doi: 10.1038/s41374-020-0475-7. Epub 2020 Jul 31.
10
Polarimetric second-harmonic generation microscopy of the hierarchical structure of collagen in stage I-III non-small cell lung carcinoma.I-III期非小细胞肺癌中胶原蛋白层次结构的偏振二次谐波生成显微镜检查
Biomed Opt Express. 2020 Mar 9;11(4):1851-1863. doi: 10.1364/BOE.387744. eCollection 2020 Apr 1.

本文引用的文献

1
Cancer statistics, 2013.癌症统计数据,2013 年。
CA Cancer J Clin. 2013 Jan;63(1):11-30. doi: 10.3322/caac.21166. Epub 2013 Jan 17.
2
Hierarchical model of fibrillar collagen organization for interpreting the second-order susceptibility tensors in biological tissue.用于解释生物组织中二阶磁化率张量的纤维状胶原组织的层次模型。
Biophys J. 2012 Nov 21;103(10):2093-105. doi: 10.1016/j.bpj.2012.10.019. Epub 2012 Nov 20.
3
Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure.二次谐波产生显微镜用于胶原纤维结构的定量分析。
Nat Protoc. 2012 Mar 8;7(4):654-69. doi: 10.1038/nprot.2012.009.
4
Nonlinear optical properties of type I collagen fibers studied by polarization dependent second harmonic generation microscopy.偏振相关二次谐波产生显微镜研究 I 型胶原纤维的非线性光学性质。
J Phys Chem B. 2011 Nov 10;115(44):12759-69. doi: 10.1021/jp206308k. Epub 2011 Oct 19.
5
Three-dimensional visualization of the first hyperpolarizability tensor.三维各向异性极化率张量的可视化。
J Comput Chem. 2011 Apr 30;32(6):1128-34. doi: 10.1002/jcc.21694. Epub 2010 Nov 19.
6
Nonlinear multicontrast microscopy of hematoxylin-and-eosin-stained histological sections.苏木精-伊红染色组织切片的非线性多对比显微镜检查。
J Biomed Opt. 2010 Mar-Apr;15(2):026018. doi: 10.1117/1.3382908.
7
Femtosecond Yb:KGd(WO(4))(2) laser oscillator pumped by a high power fiber-coupled diode laser module.由高功率光纤耦合二极管激光模块泵浦的飞秒镱:钆钨酸盐(Yb:KGd(WO(4))(2))激光振荡器
Opt Express. 2006 Dec 11;14(25):12163-8. doi: 10.1364/oe.14.012163.
8
Collagen fibril form and function.胶原纤维的形态与功能。
Adv Protein Chem. 2005;70:341-74. doi: 10.1016/S0065-3233(05)70010-3.
9
New insights into the role of extracellular matrix during tumor onset and progression.细胞外基质在肿瘤发生和进展过程中作用的新见解。
J Cell Physiol. 2002 Sep;192(3):259-67. doi: 10.1002/jcp.10142.
10
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.细胞外基质重塑增加与人类肝细胞癌的肿瘤进展相关。
Hepatology. 2001 Jul;34(1):82-8. doi: 10.1053/jhep.2001.25758.

利用二次谐波偏振显微镜对非小细胞肺癌中的胶原蛋白进行表征

Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy.

作者信息

Golaraei Ahmad, Cisek Richard, Krouglov Serguei, Navab Roya, Niu Carolyn, Sakashita Shingo, Yasufuku Kazuhiro, Tsao Ming-Sound, Wilson Brian C, Barzda Virginijus

机构信息

Department of Physics and Institute for Optical Sciences, University of Toronto, 60 Saint George Street, Toronto, ON M5S1A7, Canada ; Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON L5L1C6, Canada.

Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada.

出版信息

Biomed Opt Express. 2014 Sep 11;5(10):3562-7. doi: 10.1364/BOE.5.003562. eCollection 2014 Oct 1.

DOI:10.1364/BOE.5.003562
PMID:25360372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4206324/
Abstract

Polarization second harmonic microscopy was used for collagen imaging in human non-small cell lung carcinoma and normal lung tissues ex vivo and revealed significant differences in the nonlinear susceptibility component ratio, demonstrating potential use in cancer diagnosis.

摘要

偏振二次谐波显微镜用于对人非小细胞肺癌和正常肺组织进行离体胶原成像,并揭示了非线性磁化率分量比率的显著差异,证明其在癌症诊断中的潜在用途。