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重新评估医学实践中的安慰剂效应。

Reevaluating the placebo effect in medical practice.

作者信息

Colloca Luana, Jonas Wayne B, Killen John, Miller Franklin G, Shurtleff David

机构信息

National Center for Complementary and Alternative Medicine (NCCAM), Bethesda, MD, USA.

National Institute of Mental Health (NIMH), Bethesda, MD, USA.

出版信息

Z Psychol. 2014;222(3):124-127. doi: 10.1027/2151-2604/a000177.

Abstract

Recent findings on placebo research corroborate the evidence that the placebo effect represents a promising model to shed new light on the brain-mind-body interactions. In particular, this research has partially elucidated the role of how patients' expectations and the quality of physician-patient communication can influence the efficacy of interventions and overall clinical outcomes. Accordingly, the study of the placebo effect should be incorporated in the core clinical practice curriculum of all health practitioners. While the growing knowledge of the placebo effect points to it as an irreducible primary reality of the medical sciences, an ethical analysis aimed at avoiding the misuse of placebos is needed, while maximizing the opportunity for beneficial placebo effects.

摘要

安慰剂研究的最新发现证实了这样的证据,即安慰剂效应是一个很有前景的模型,能为脑-心-身相互作用带来新的启示。特别是,这项研究部分阐明了患者期望以及医患沟通质量如何影响干预效果和整体临床结果。因此,安慰剂效应的研究应纳入所有医疗从业者核心临床实践课程。虽然对安慰剂效应的认识不断增加,表明它是医学科学中不可简化的基本现实,但仍需要进行伦理分析,以避免安慰剂的滥用,同时最大限度地发挥有益安慰剂效应的机会。

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本文引用的文献

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Placebo analgesia: clinical applications.安慰剂镇痛:临床应用
Pain. 2014 Jun;155(6):1055-1058. doi: 10.1016/j.pain.2013.12.007. Epub 2013 Dec 11.
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Placebo analgesia: psychological and neurobiological mechanisms.安慰剂镇痛:心理和神经生物学机制。
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Harnessing the placebo effect: the need for translational research.利用安慰剂效应:转化研究的必要性。
Philos Trans R Soc Lond B Biol Sci. 2011 Jun 27;366(1572):1922-30. doi: 10.1098/rstb.2010.0399.
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Placebo interventions, placebo effects and clinical practice.安慰剂干预、安慰剂效应与临床实践。
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