van Hoek Ingrid, Hesta Myriam, Biourge Vincent
Royal Canin Research & Development Center, Aimargues, France
Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium.
J Feline Med Surg. 2015 Oct;17(10):837-47. doi: 10.1177/1098612X14556558. Epub 2014 Nov 3.
Since the first description of feline hyperthyroidism (HT) in 1979, several studies have been undertaken to define the etiology of the disease. Epidemiologic studies, after investigating non-food- and food-associated factors, suggest a multifactorial etiology. However, in the absence of prospective cohort studies that can confirm a cause-and-effect relationship between HT and associated risk factors, no causative factor for HT has been identified to date. Feline HT resembles toxic nodular goiter in humans, with autonomously functioning upregulated iodide uptake systems. Contribution of the diet to HT development remains controversial. The purpose of this paper is to review critically the reported food-associated risk factors for HT.
自1979年首次描述猫甲状腺功能亢进症（HT）以来，已经开展了多项研究来确定该疾病的病因。流行病学研究在调查了与食物和非食物相关的因素后，提示其病因是多因素的。然而，由于缺乏能够证实HT与相关风险因素之间因果关系的前瞻性队列研究，迄今为止尚未确定HT的致病因素。猫HT类似于人类的毒性结节性甲状腺肿，具有自主功能上调的碘摄取系统。饮食对HT发生发展的作用仍存在争议。本文的目的是严格审查已报道的与食物相关的HT风险因素。
