Ahaneku Gladys Ifesinachi, Ahaneku Joseph Eberendu, Osuji Charles Ukachukwu, Oguejiofor Celestine Ogonna, Opara Patience Chioma
Department of Medicine Nnamdi Azikiwe University and Teaching Hospital, Nnewi Campus, Nigeria.
Chemical Pathology, Nnamdi Azikiwe University and Teaching Hospital, Nnewi Campus, Nigeria.
Pan Afr Med J. 2014 May 10;18:37. doi: 10.11604/pamj.2014.18.37.1926. eCollection 2014.
Demonstration of cardiovascular disease (CVD) markers in healthy subjects with normal blood chemistry tests underscores the need to study social determinants of risk factors to aid primary prevention worldwide; particularly in slums which harbor nearly 80% of rural to urban migrants in the epidemiologically transiting Africa where CVDs were previously unknown. The objective of this study was to assess lipids in relationship to alcohol consumption and BMI in a Nigerian slum.
Cross sectional community based prevalent study involving 191 apparently healthy inhabitants aged 18-85 years recruited by convenient sampling. Heights, weights and BMIs were measured/ calculated, venous blood samples collected and lipid analysis done procedurally. Excel 13 and SPSS statistical soft ware were used for analysis and chart representation.
THEIR MEAN PARAMETERS WERE: Age (43.87±1.62 years), triglycerides (TG; 1.20±0.08 mmol/L), total Cholesterol (TC; 4.54±1.70 mmol/L), low density lipoprotein cholesterol (LDLC; 3.69±1.69 mmol/L), high density lipoprotein cholesterol (HDLC; 0.61±0.24 mmol/L), RPI (7.12±5.24), body mass index (BMI; 25.08±5.18 Kg/M2). TG and HDLC values were lowest in obese non alcohol drinkers while all other lipid parameters increased with BMI in both drinkers and non drinkers. Low HDLC prevalence was lowest in obese alcohol drinkers and highest (100%) in their non drinking counterparts. Having favourable HDLC was highest in daily alcohol consumers. No weekly drinker (0%) had favourable HDLC.
Ignorance, poor nutritional and health education may be major factors in the strategic challenge posed by the emergence of non communicable diseases in Africans.
在血液化学检测正常的健康受试者中发现心血管疾病(CVD)标志物,凸显了研究危险因素的社会决定因素以助力全球一级预防的必要性;尤其是在贫民窟,在以前未知心血管疾病的处于流行病学转变期的非洲,近80%的农村到城市移民居住在那里。本研究的目的是评估尼日利亚一个贫民窟中脂质与饮酒及体重指数(BMI)的关系。
采用方便抽样法,对191名年龄在18 - 85岁、表面健康的居民进行基于社区的横断面现况研究。测量/计算身高、体重和BMI,按程序采集静脉血样本并进行脂质分析。使用Excel 13和SPSS统计软件进行分析和图表展示。
他们的平均参数为:年龄(43.87±1.62岁)、甘油三酯(TG;1.20±0.08 mmol/L)、总胆固醇(TC;4.54±1.70 mmol/L)、低密度脂蛋白胆固醇(LDLC;3.69±1.69 mmol/L)、高密度脂蛋白胆固醇(HDLC;0.61±0.24 mmol/L)、相对病理指数(RPI;7.12±5.24)、体重指数(BMI;25.08±5.18 Kg/M2)。肥胖不饮酒者的TG和HDLC值最低,而在饮酒者和不饮酒者中,所有其他脂质参数均随BMI升高。肥胖饮酒者中低HDLC患病率最低,其不饮酒的对应人群中患病率最高(100%)。每日饮酒者中具有良好HDLC的比例最高。每周饮酒者中无人(0%)具有良好HDLC。
无知、不良的营养和健康教育可能是非洲人非传染性疾病出现所带来的战略挑战中的主要因素。