Kamp Siri-Maria, Donchin Emanuel
Department of Psychology, Saarland University, Saarbrücken, Germany.
Psychophysiology. 2015 Apr;52(4):460-71. doi: 10.1111/psyp.12378. Epub 2014 Nov 4.
We investigated the relationship between, and functional significance of, P300, novelty P3, and the pupil dilation response (PDR). Subjects categorized stimuli including (a) words of a frequent category, (b) words of an infrequent category (14%), and (c) pictures of the frequent category ("novels"; 14%). The P300 and novelty P3 were uncorrelated with the PDR and differed in their response to experimental manipulation. Therefore, although the three physiological responses often co-occur, they appear to each manifest a distinct function: The PDR may be more closely linked to aspects of behavioral responding than the event-related potentials. Within participants, P300 and PDR latencies accounted for unique portions of the reaction time variance, and amplitudes of all three responses were larger for stimuli recalled on a subsequent test, compared to not recalled. We discuss the possibility that all three responses reflect norepinephric input from the locus coeruleus.
我们研究了P300、新奇P3和瞳孔扩张反应（PDR）之间的关系及其功能意义。受试者对刺激进行分类，包括（a）常见类别的单词，（b）不常见类别的单词（14%），以及（c）常见类别的图片（“新奇图片”；14%）。P300和新奇P3与PDR不相关，且对实验操作的反应不同。因此，尽管这三种生理反应经常同时出现，但它们似乎各自表现出独特的功能：与事件相关电位相比，PDR可能与行为反应的各个方面联系更紧密。在参与者内部，P300和PDR潜伏期占反应时间方差的独特部分，并且与未被回忆起的刺激相比，所有三种反应的幅度在随后的测试中对被回忆起的刺激更大。我们讨论了这三种反应均反映来自蓝斑的去甲肾上腺素输入的可能性。
