Vidal-Liñán Leticia, Bellas Juan, Fumega José, Beiras Ricardo
Departamento de Ecoloxía e Bioloxía Animal, Universidade de Vigo, Estrada Colexio Universitario s/n, 36310, Vigo, Galicia, Spain,
Ecotoxicology. 2015 Mar;24(2):292-300. doi: 10.1007/s10646-014-1377-5. Epub 2014 Nov 6.
Mussels, Mytilus galloprovincialis, showed a high bioaccumulation ability when exposed to waterborne tetrabromodiphenyl ether (BDE-47), with a bioconcentration factor of 10,900 L Kg(-1) wet weight, and slow depuration rates in clean seawater. Kinetic and concentration-response experiments were performed measuring in the exposed mussel the activities of three molecular biomarkers: glutathione S-transferase (GST), glutathione peroxidase (GPx) and acetylcholinesterase (AChE). The long term (30 days) exposure of mussels to all concentrations (2-15 µg L(-1)) of BDE-47 significantly inhibited the AChE and GST activities, a result that supports the suitability of these biomarkers in marine pollution monitoring programs. However, GPx activity showed a less consistent pattern of response depending on the concentration and the duration of exposure.
贻贝（Mytilus galloprovincialis）在接触水体中的四溴二苯醚（BDE - 47）时表现出较高的生物累积能力，其生物浓缩系数为10,900 L Kg⁻¹湿重，并且在清洁海水中的净化速率较慢。进行了动力学和浓度响应实验，测量暴露贻贝中三种分子生物标志物的活性：谷胱甘肽S - 转移酶（GST）、谷胱甘肽过氧化物酶（GPx）和乙酰胆碱酯酶（AChE）。贻贝长期（30天）暴露于所有浓度（2 - 15 µg L⁻¹）的BDE - 47中，显著抑制了AChE和GST的活性，这一结果支持了这些生物标志物在海洋污染监测项目中的适用性。然而，GPx活性根据暴露浓度和持续时间显示出不太一致的响应模式。
