Zhang Yue, Chen Xue-Min, Sun Dong-Lin
Department of Hepatobiliary Surgery, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.
World J Surg Oncol. 2014 Nov 5;12:327. doi: 10.1186/1477-7819-12-327.
This study was designed to compare clinical outcomes for laparoscopic distal pancreatectomy (LDP) and open distal pancreatectomy (ODP) performed at a single institution.
This retrospective study included 43 patients who underwent distal pancreatectomy between 2009 and 2013. The patients were divided into two groups based on the surgical approach: the laparoscopic surgery group (n=20) and the open surgery group (n=23). All clinical data were analyzed retrospectively.
There were no significant differences in operation time, rate of intraoperative transfusions, complications, or mortality between the two groups. The intraoperative blood loss (210±84.4 mL vs. 420±91.1 mL), first flatus time (1.5±1 d vs. 4±2.5 d), diet start time (2±0.7 d vs. 6±1.8 d), and postoperative hospital stay (8±3.5 d vs. 14±5.5 d) were significantly less in the LDP group than in the ODP group. All patients had negative surgical margins at final pathology. There were no significant differences in the number of lymph nodes harvested (10±2.1 vs. 11±3.2) between the two groups.
LDP is a feasible and safe surgical approach as well as ODP, but has the advantages of an earlier return to normal bowel movements, normal diet, and shorter hospital stays than ODP.
本研究旨在比较在单一机构进行的腹腔镜远端胰腺切除术（LDP）和开放远端胰腺切除术（ODP）的临床结果。
这项回顾性研究纳入了2009年至2013年间接受远端胰腺切除术的43例患者。根据手术方式将患者分为两组：腹腔镜手术组（n = 20）和开放手术组（n = 23）。所有临床数据均进行回顾性分析。
两组在手术时间、术中输血率、并发症或死亡率方面无显著差异。LDP组的术中失血量（210±84.4 mL对420±91.1 mL）、首次排气时间（1.5±1天对4±2.5天）、开始进食时间（2±约0.7天对6±1.8天）和术后住院时间（8±3.5天对14±5.5天）均显著少于ODP组。所有患者最终病理检查手术切缘均为阴性。两组之间清扫的淋巴结数量无显著差异（10±2.1对11±3.2）。
LDP与ODP一样是一种可行且安全的手术方法，但与ODP相比，具有更早恢复正常排便、正常饮食和更短住院时间的优势。
