HKUST-Shenzhen Research Institute, No. 9 Yuexing 1st RD, South Area, Hi-Tech Park, Nanshan, Shenzhen 518057, China.
Chem Soc Rev. 2015 Jul 7;44(13):4228-38. doi: 10.1039/c4cs00325j. Epub 2014 Nov 6.
Fluorescent biosensors are powerful analytical tools for studying biological events in living systems. Luminescent materials with aggregation-induced emission (AIE) attributes have attracted much research interest and have been identified as a novel class of luminogens to develop fluorescent turn-on biosensors with superior sensitivity. In this Tutorial Review, we present an overview of the AIE phenomenon and its mechanism. We summarize the structural design and working principle of AIE biosensors developed recently. Typical examples of AIE biosensors are presented.
荧光生物传感器是研究活系统中生物事件的有力分析工具。具有聚集诱导发射（AIE）特性的发光材料引起了广泛的研究兴趣，并已被确定为一类新型发光团，用于开发具有优异灵敏度的荧光开启型生物传感器。在本综述中，我们介绍了 AIE 现象及其机制的概述。我们总结了最近开发的 AIE 生物传感器的结构设计和工作原理。展示了 AIE 生物传感器的典型实例。
