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基于 MRI 半定量分级方法评估膝关节骨关节炎软骨丢失的危险因素研究进展。

An update on risk factors for cartilage loss in knee osteoarthritis assessed using MRI-based semiquantitative grading methods.

机构信息

Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA.

出版信息

Eur Radiol. 2015 Mar;25(3):883-93. doi: 10.1007/s00330-014-3464-7. Epub 2014 Nov 7.

DOI:10.1007/s00330-014-3464-7
PMID:25377771
Abstract

Arthroscopy-based semiquantitative scoring systems such as Outerbridge and Noyes' scores were the first to be developed for the purpose of grading cartilage defects. As magnetic resonance imaging (MRI) became available for evaluation of the osteoarthritic knee joint, these systems were adapted for use with MRI. Later on, grading methods such as the Whole Organ Magnetic Resonance Score, the Boston-Leeds Osteoarthritis Knee Score and the MRI Osteoarthritis Knee Score were designed specifically for performing whole-organ assessment of the knee joint structures, including cartilage. Cartilage grades on MRI obtained with these scoring systems represent optimal outcome measures for longitudinal studies, and are designed to enhance understanding of the knee osteoarthritis disease process. The purpose of this narrative review is to describe cartilage assessment in knee osteoarthritis using currently available MRI-based semiquantitative whole-organ scoring systems, and to provide an update on the risk factors for cartilage loss in knee osteoarthritis as assessed with these scoring systems.

摘要

基于关节镜的半定量评分系统,如 Outerbridge 和 Noyes 评分,是为了对软骨缺陷进行分级而首先开发的。随着磁共振成像(MRI)可用于评估骨关节炎膝关节,这些系统也被改编用于 MRI。后来,全器官磁共振评分、波士顿-利兹骨关节炎膝关节评分和 MRI 骨关节炎膝关节评分等分级方法专门用于对膝关节结构(包括软骨)进行全器官评估。这些评分系统获得的 MRI 上的软骨分级是进行纵向研究的最佳结果指标,旨在增强对膝关节骨关节炎疾病过程的理解。本叙述性综述的目的是描述目前可用的基于 MRI 的半定量全器官评分系统在膝关节骨关节炎中的软骨评估,并提供这些评分系统评估的膝关节骨关节炎软骨丢失的危险因素的最新信息。

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本文引用的文献

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The relationship between subchondral sclerosis detected with MRI and cartilage loss in a cohort of subjects with knee pain: the knee osteoarthritis progression (KOAP) study.MRI 检测到的软骨下硬化与膝关节疼痛患者队列中软骨丢失的关系:膝骨关节炎进展(KOAP)研究。
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