Imaging Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195.
Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
AJR Am J Roentgenol. 2020 Aug;215(2):441-447. doi: 10.2214/AJR.19.22285. Epub 2020 May 6.
Cartilage loss on preoperative knee MRI is a predictor of poor outcomes after arthroscopic partial meniscectomy. The purpose of this study was to compare the ability to predict outcomes after arthroscopic partial meniscectomy with a clinically used modified Outerbridge system versus a semiquantitative MRI Osteoarthritis Knee Score system for grading cartilage loss. Patients who underwent preoperative knee MRI within 6 months of arthroscopic partial meniscectomy and who had outcomes available from the time of surgery and 1 year later were eligible for inclusion. Cases were evaluated by two radiologists and one radiology fellow with the use of both grading systems. The accuracy of each system in discriminating between surgical success and failure was estimated using the ROC curve (AUC) with 95% CIs. A Wald test was used to assess noninferiority of the clinical grading system. Interreader agreement regarding the accuracy of the grading systems in predicting outcomes was also compared. A total of 78 patients (38 women and 40 men; mean age, 56.6 years) were included in the study. A prediction model using clinical grading (AUC = 0.695; 95% CI, 0.566-0.824) was noninferior ( = 0.047) to a model using MRI Osteoarthritis Knee Score grading (AUC = 0.683; 95% CI, 0.539-0.827). Both MRI prediction models performed better than a model using demographic characteristics only (AUC = 0.667; 95% CI, 0.522-0.812). Inter-reader agreement with clinical grading (80.8%) was higher than that with MRI Osteoarthritis Knee Score grading (65.0%; = 0.012). A clinically used system to grade cartilage loss on MRI is as effective as a semiquantitative system for predicting outcomes after arthroscopic partial meniscectomy, while also offering improved interreader agreement.
术前膝关节 MRI 上的软骨损失是关节镜下部分半月板切除术预后不良的预测指标。本研究的目的是比较一种临床上使用的改良 Outerbridge 系统与半定量 MRI 骨关节炎膝关节评分系统评估软骨损失分级来预测关节镜下部分半月板切除术后结果的能力。符合纳入标准的患者为在关节镜下部分半月板切除术前 6 个月内行膝关节 MRI 检查,且术后及 1 年时均有结局数据。由两位放射科医生和一位放射科住院医师使用两种分级系统对病例进行评估。使用 ROC 曲线(AUC)及其 95%CI 来估计每种系统区分手术成功与失败的准确性。使用 Wald 检验来评估临床分级系统的非劣效性。还比较了两种分级系统预测结果的准确性的读者间一致性。
共有 78 例患者(38 名女性和 40 名男性;平均年龄 56.6 岁)纳入研究。使用临床分级的预测模型(AUC = 0.695;95%CI,0.566-0.824)是非劣效( = 0.047)于使用 MRI 骨关节炎膝关节评分分级的预测模型(AUC = 0.683;95%CI,0.539-0.827)。两种 MRI 预测模型均优于仅使用人口统计学特征的模型(AUC = 0.667;95%CI,0.522-0.812)。使用临床分级的读者间一致性(80.8%)高于使用 MRI 骨关节炎膝关节评分分级的读者间一致性(65.0%; = 0.012)。
一种临床上使用的系统来评估 MRI 上的软骨损失与一种半定量系统在预测关节镜下部分半月板切除术后结果方面同样有效,同时还提高了读者间一致性。