对经过运动训练的小鼠进行发光二极管疗法可提高肌肉性能、细胞色素c氧化酶活性、三磷酸腺苷（ATP）水平并促进细胞增殖。
Light-emitting diode therapy in exercise-trained mice increases muscle performance, cytochrome c oxidase activity, ATP and cell proliferation.
作者信息
Ferraresi Cleber, Parizotto Nivaldo Antonio, Pires de Sousa Marcelo Victor, Kaippert Beatriz, Huang Ying-Ying, Koiso Tomoharu, Bagnato Vanderlei Salvador, Hamblin Michael R
机构信息
Laboratory of Electrothermophototherapy, Department of Physical Therapy, Federal University of Sao Carlos, SP, Brazil.
Post-Graduation Program in Biotechnology, Federal University of Sao Carlos, SP, Brazil.
出版信息
J Biophotonics. 2015 Sep;8(9):740-54. doi: 10.1002/jbio.201400087. Epub 2014 Nov 6.
Abstract
Light-emitting diode therapy (LEDT) applied over the leg, gluteus and lower-back muscles of mice using a LED cluster (630 nm and 850 nm, 80 mW/cm(2) , 7.2 J/cm(2) ) increased muscle performance (repetitive climbing of a ladder carrying a water-filled tube attached to the tail), ATP and mitochondrial metabolism; oxidative stress and proliferative myocyte markers in mice subjected to acute and progressive strength training. Six bi-daily training sessions LEDT-After and LEDT-Before-After regimens more than doubled muscle performance and increased ATP more than tenfold. The effectiveness of LEDT on improving muscle performance and recovery suggest applicability for high performance sports and in training programs. Positioning of the mice and light-emitting diode therapy (LEDT) applied on mouse legs, gluteus and lower-back muscles without contact.
摘要
使用发光二极管集群（630纳米和850纳米，80毫瓦/平方厘米，7.2焦耳/平方厘米）对小鼠腿部、臀部和下背部肌肉进行发光二极管疗法（LEDT），可提高肌肉性能（携带连接在尾巴上的装满水的管子重复攀爬梯子）、ATP和线粒体代谢；在接受急性和渐进性力量训练的小鼠中，可降低氧化应激并增加增殖性肌细胞标志物。LEDT-训练后和LEDT-训练前-训练后方案的每日两次训练疗程，使肌肉性能提高了一倍多，ATP增加了十多倍。LEDT在改善肌肉性能和恢复方面的有效性表明其适用于高性能运动和训练计划。小鼠的定位以及对小鼠腿部、臀部和下背部肌肉进行的发光二极管疗法（LEDT）无需接触。
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