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[转移性睾丸肿瘤患者化疗引起的胸腺变化的计算机断层扫描检测]

[Computed tomographic detection of chemotherapy-induced thymus changes in patients with metastatic testicular tumors].

作者信息

Hendrickx P, Döhring W

机构信息

Abteilung Diagnostische Radiologie, Medizinische Hochschule Hannover.

出版信息

Rofo. 1989 Mar;150(3):268-73. doi: 10.1055/s-2008-1047021.

DOI:10.1055/s-2008-1047021
PMID:2538874
Abstract

Serial thoracic CT scans of 100 patients suffering from testicular cancer revealed that the thymus appears to atrophy temporarily during administration of cytostatic agents. About two months after cessation of chemotherapy rebound enlargement of the thymus occurs and persists for about two years followed by a slow involution. Using a semiquantitative score system, thymic CT images of these patients were compared with that of 100 patients suffering from other malignancies, 100 patients without malignant disease and 52 patients with myasthenia gravis, taking into account the age-related changes of the size of the organ. Rebound thymic enlargement should not be misinterpreted as metastatic lymph nodes.

摘要

对100例睾丸癌患者进行的胸部CT连续扫描显示,在使用细胞抑制剂期间,胸腺似乎会暂时萎缩。化疗停止约两个月后,胸腺会出现反弹性增大,并持续约两年,随后缓慢退化。使用半定量评分系统,将这些患者的胸腺CT图像与100例其他恶性肿瘤患者、100例无恶性疾病患者和52例重症肌无力患者的图像进行比较,同时考虑到器官大小与年龄相关的变化。胸腺反弹性增大不应被误诊为转移性淋巴结。

相似文献

1
[Computed tomographic detection of chemotherapy-induced thymus changes in patients with metastatic testicular tumors].[转移性睾丸肿瘤患者化疗引起的胸腺变化的计算机断层扫描检测]
Rofo. 1989 Mar;150(3):268-73. doi: 10.1055/s-2008-1047021.
2
[Thymus hyperplasia in patients with malignant testicular tumors].[恶性睾丸肿瘤患者的胸腺增生]
Med Klin (Munich). 1990 Feb 15;85(2):72-7.
3
Thymic atrophy and rebound enlargement following chemotherapy for testicular cancer.
Acta Radiol. 1989 May-Jun;30(3):263-7.
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Benign thymic enlargement in adults after chemotherapy: CT demonstration.成人化疗后良性胸腺增大:CT表现
Radiology. 1987 Apr;163(1):67-70. doi: 10.1148/radiology.163.1.3823458.
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Thymic hyperplasia after adjuvant chemotherapy in breast cancer.乳腺癌辅助化疗后的胸腺增生
J Thorac Imaging. 2006 Mar;21(1):43-6. doi: 10.1097/01.rti.0000185143.17436.f9.
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[Reactive benign thymus hyperplasia following cytostatic chemotherapy].[细胞毒性化疗后反应性良性胸腺增生]
Dtsch Med Wochenschr. 1988 Apr 15;113(15):598-601. doi: 10.1055/s-2008-1067689.
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[Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma].[儿童恶性淋巴瘤化疗后反应性胸腺增生的临床分析]
Ai Zheng. 2006 Apr;25(4):471-5.
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Thymic hyperplasia after chemotherapy: two case reports and a literature review.化疗后胸腺增生:两例病例报告及文献综述
Indiana Med. 1991 Sep;84(9):624-7.
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Thymic rebound in an adult following chemotherapy for testicular cancer.一名成年男性睾丸癌化疗后的胸腺反跳现象。
Eur J Surg Oncol. 1986 Dec;12(4):385-7.
10
[Urologic treatment of testicular germ cell cancer].睾丸生殖细胞癌的泌尿外科治疗
Arch Esp Urol. 2002 Oct;55(8):927-36.

引用本文的文献

1
[Chemotherapy definitions and policies for thymic malignancies].[胸腺恶性肿瘤的化疗定义及策略]
Zhongguo Fei Ai Za Zhi. 2014 Feb;17(2):116-21. doi: 10.3779/j.issn.1009-3419.2014.02.09.