Murphy B R, Conces D J, Nichols C R
Department of Medicine, Indiana University School of Medicine, Indianapolis.
Indiana Med. 1991 Sep;84(9):624-7.
The development of mediastinal masses in patients previously treated for cancer frequently indicates recurrent or metastatic disease. In this article we describe two patients previously treated for malignancies who had new or recurrent anterior mediastinal masses. These masses proved to be markedly enlarged thymuses due to thymic hyperplasia. The development of thymic hyperplasia after systemic chemotherapy is an uncommon but well known phenomenon. The management of such patients includes close observation or surgical intervention. Empiric antineoplastic therapy is not indicated.
曾接受过癌症治疗的患者出现纵隔肿块，往往提示疾病复发或转移。在本文中，我们描述了两名曾接受过恶性肿瘤治疗的患者，他们出现了新的或复发的前纵隔肿块。这些肿块经证实是由于胸腺增生导致胸腺明显增大。全身化疗后发生胸腺增生是一种罕见但广为人知的现象。对此类患者的处理包括密切观察或手术干预。不建议进行经验性抗肿瘤治疗。
