Ash Anthony, Mulholland Francis, Burnett Gary R, Wilde Peter J
a Institute of Food Research , Colney , Norwich , UK.
Biofouling. 2014;30(10):1183-97. doi: 10.1080/08927014.2014.977268.
Sodium dodecyl sulphate (SDS) and sodium tripolyphosphate (STP) act to remove stained pellicle from dentition and loosen deposits on tooth surfaces that may become cariogenic over time. This study investigated how SDS and STP impact the salivary pellicle adsorbed onto hydroxyapatite and silica sensors using a dual polarisation interferometer and a quartz-crystal microbalance with dissipation. After the pellicle was exposed to SDS and STP the remaining pellicle, although weaker, due to the loss of material, became less dense but with a higher elastic component; suggesting that the viscous component of the pellicle was being removed. This would imply a structural transformation from a soft but dense structured pellicle, to a more diffuse pellicle. In addition, the majority of proteins displaced by both SDS and STP were identified as being acidic in nature; implying that the negatively charged groups of SDS and STP may be responsible for the displacement of the pellicle proteins observed.
十二烷基硫酸钠（SDS）和三聚磷酸钠（STP）的作用是去除牙列上的染色薄膜，并疏松牙齿表面随着时间推移可能会导致龋齿的沉积物。本研究使用双偏振干涉仪和带耗散的石英晶体微天平，研究了SDS和STP如何影响吸附在羟基磷灰石和二氧化硅传感器上的唾液薄膜。在薄膜暴露于SDS和STP后，剩余的薄膜虽然由于材料损失而变弱，但密度变小但弹性成分更高；这表明薄膜的粘性成分正在被去除。这意味着从柔软但致密结构的薄膜转变为更分散的薄膜。此外，被SDS和STP置换的大多数蛋白质在性质上被鉴定为酸性；这意味着SDS和STP带负电荷的基团可能是观察到的薄膜蛋白质置换的原因。
