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本文引用的文献

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Prevalence of childhood obesity and hypertension in south of Iran.伊朗南部儿童肥胖和高血压的患病率
Iran J Kidney Dis. 2013 Jul;7(4):282-9.
2
Anthropometric measures and blood pressure in school children.学生的人体测量指标与血压。
J Pediatr (Rio J). 2013 May-Jun;89(3):243-9. doi: 10.1016/j.jped.2012.11.006. Epub 2013 Apr 26.
3
Hypertriglyceridemic waist phenotype: association with metabolic abnormalities in adolescents.高三酰甘油性腰围表型:与青少年代谢异常的相关性。
J Pediatr (Rio J). 2013 Jan-Feb;89(1):56-63. doi: 10.1016/j.jped.2013.02.009.
4
The role of non-HDL cholesterol in risk stratification for coronary artery disease.非高密度脂蛋白胆固醇在冠状动脉疾病风险分层中的作用。
Curr Atheroscler Rep. 2012 Apr;14(2):130-4. doi: 10.1007/s11883-011-0224-x.
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Trends in risk factors for cardiovascular disease among Iranian adolescents: the Tehran Lipid and Glucose Study, 1999-2008.伊朗青少年心血管疾病风险因素的变化趋势:1999-2008 年德黑兰血脂和血糖研究。
J Epidemiol. 2011;21(5):319-28. doi: 10.2188/jea.JE20100162. Epub 2011 Jul 30.
6
Hypertriglyceridemic waist: a simple clinical phenotype associated with coronary artery disease in women.高三酰甘油血症性腰围:一种与女性冠心病相关的简单临床表型。
Metabolism. 2012 Jan;61(1):56-64. doi: 10.1016/j.metabol.2011.05.017. Epub 2011 Jul 5.
7
Associated factors to total cholesterol: school based study in southern Brazil.总胆固醇相关因素:巴西南部的一项基于学校的研究。
Arq Bras Cardiol. 2011 Jul;97(1):17-25. doi: 10.1590/s0066-782x2011005000065. Epub 2011 May 27.
8
Adiposity, biological markers of disease, and insulin resistance in Mexican American adolescents, 2004-2005.墨西哥裔美国青少年的肥胖、疾病生物标志物和胰岛素抵抗,2004-2005 年。
Prev Chronic Dis. 2011 Mar;8(2):A40. Epub 2011 Feb 15.
9
Prevalence and anthropometric predictors of high blood pressure in schoolchildren from João Pessoa - PB, Brazil.巴西若昂佩索阿市儿童高血压的流行状况及人体测量学预测因素。
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Diagnosis and classification of diabetes mellitus.糖尿病的诊断与分类
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巴西学童的高甘油三酯血症腰围与代谢异常

Hypertriglyceridemic waist and metabolic abnormalities in Brazilian schoolchildren.

作者信息

Guilherme Flávio Ricardo, Molena-Fernandes Carlos Alexandre, Hintze Luzia Jaeger, Fávero Maria Teresa Martins, Cuman Roberto Kenji Nakamura, Rinaldi Wilson

机构信息

Department of Physical Education, State University of Maringa, Parana, Brazil.

Laboratory of Inflammation, Department of Pharmacy and Pharmacology, State University of Maringa, Maringa, Parana, Brazil.

出版信息

PLoS One. 2014 Nov 14;9(11):e111724. doi: 10.1371/journal.pone.0111724. eCollection 2014.

DOI:10.1371/journal.pone.0111724
PMID:25397885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4232366/
Abstract

OBJECTIVE

To identify the prevalence of hypertriglyceridemic waist (HTW) phenotype and its association with metabolic abnormalities in schoolchildren.

METHODS

A cross-sectional study, with a sample of 241 students aged 10 to 14 years from public schools (4 schools) and private (2 schools) from Paranavai town, in Parana State, Brazil. Anthropometric variables (weight, height, waist circumference) and levels of triglycerides, total cholesterol, HDL-C, non-HDL and LDL-C were analyzed. In statistical tests of Pearson partial correlation and multivariate logistic regression, considering p<0,05.

RESULTS

The prevalence of HTW was 20,7% among schoolchildren, 14,1% in males and 6,6% among females with higher proportions aged 10-12 years old. Multivariate analysis indicated that the students who attended private schools were nearly three times more likely (95% CI: 1,2-5,6), to be diagnosed with HTW compared with those who attended public schools (p = 0,006), and LDL-C was the only metabolic variable positively associated with the outcome (p = 0,001), where the students categorized with elevated serum levels had odds 4,2 times (95% CI: 1,6-10,9) having the HTW compared to students in appropriate levels.

CONCLUSION

This study showed higher prevalence of hypertriglyceridemic waist phenotype in students when compared to prospective studies in Brazil and worldwide. It also showed that the only metabolic alteration associated with HTW phenotype was LDL-C (low density lipoprotein).

摘要

目的

确定学龄儿童中高甘油三酯血症腰围(HTW)表型的患病率及其与代谢异常的关联。

方法

一项横断面研究,样本来自巴西巴拉那州帕拉纳瓦伊镇的公立学校(4所)和私立学校(2所)的241名10至14岁学生。分析人体测量变量(体重、身高、腰围)以及甘油三酯、总胆固醇、高密度脂蛋白胆固醇、非高密度脂蛋白和低密度脂蛋白胆固醇水平。在Pearson偏相关和多变量逻辑回归统计检验中,以p<0.05为标准。

结果

学龄儿童中HTW的患病率为20.7%,男性为14.1%,女性为6.6%,10至12岁年龄段的比例更高。多变量分析表明,与就读公立学校的学生相比,就读私立学校的学生被诊断为HTW的可能性几乎高出三倍(95%置信区间:1.2 - 5.6)(p = 0.006),低密度脂蛋白胆固醇是与该结果呈正相关的唯一代谢变量(p = 0.001),血清水平升高的学生患HTW的几率是水平正常学生的4.2倍(95%置信区间:1.6 - 10.9)。

结论

与巴西和全球的前瞻性研究相比,本研究显示学生中高甘油三酯血症腰围表型的患病率更高。研究还表明,与HTW表型相关的唯一代谢改变是低密度脂蛋白胆固醇。