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肠道子宫内膜异位症:多学科手术团队中结直肠外科医生的观点

Bowel endometriosis: colorectal surgeon's perspective in a multidisciplinary surgical team.

作者信息

Wolthuis Albert M, Meuleman Christel, Tomassetti Carla, D'Hooghe Thomas, de Buck van Overstraeten Anthony, D'Hoore André

机构信息

Albert M Wolthuis, Anthony de Buck van Overstraeten, André D'Hoore, Department of Abdominal Surgery, University Hospital Leuven, Leuven 3000, Belgium.

出版信息

World J Gastroenterol. 2014 Nov 14;20(42):15616-23. doi: 10.3748/wjg.v20.i42.15616.

Abstract

Endometriosis is a gynecological condition that presents as endometrial-like tissue outside the uterus and induces a chronic inflammatory reaction. Up to 15% of women in their reproductive period are affected by this condition. Deep endometriosis is defined as endometriosis located more than 5 mm beneath the peritoneal surface. This type of endometriosis is mostly found on the uterosacral ligaments, inside the rectovaginal septum or vagina, in the rectosigmoid area, ovarian fossa, pelvic peritoneum, ureters, and bladder, causing a distortion of the pelvic anatomy. The frequency of bowel endometriosis is unknown, but in cases of bowel infiltration, about 90% are localized on the sigmoid colon or the rectum. Colorectal involvement results in alterations of bowel habits such as constipation, diarrhea, tenesmus, dyschezia, and, rarely, rectal bleeding. Differential diagnosis must be made in case of irritable bowel syndrome, solitary rectal ulcer syndrome, and a rectal tumor. A precise diagnosis about the presence, location, and extent of endometriosis is necessary to plan surgical treatment. Multidisciplinary laparoscopic treatment has become the standard of care. Depending on the size of the lesion and site of involvement, full-thickness disc excision or bowel resection needs to be performed by an experienced colorectal surgeon. Long-term outcomes, following bowel resection for severe endometriosis, regarding pain and recurrence rate are good with a pregnancy rate of 50%.

摘要

子宫内膜异位症是一种妇科疾病,表现为子宫外出现类似子宫内膜的组织,并引发慢性炎症反应。育龄期女性中高达15%受此疾病影响。深部子宫内膜异位症定义为位于腹膜表面以下超过5毫米的子宫内膜异位症。这种类型的子宫内膜异位症大多见于子宫骶韧带、直肠阴道隔或阴道内、直肠乙状结肠区域、卵巢窝、盆腔腹膜、输尿管和膀胱,导致盆腔解剖结构变形。肠道子宫内膜异位症的发生率尚不清楚,但在肠道浸润的病例中,约90%局限于乙状结肠或直肠。结直肠受累会导致排便习惯改变,如便秘、腹泻、里急后重、排便困难,很少出现直肠出血。在出现肠易激综合征、孤立性直肠溃疡综合征和直肠肿瘤的情况下必须进行鉴别诊断。为了规划手术治疗,有必要对子宫内膜异位症的存在、位置和范围做出准确诊断。多学科腹腔镜治疗已成为标准治疗方法。根据病变大小和受累部位,需要由经验丰富的结直肠外科医生进行全层椎间盘切除或肠切除。对于严重子宫内膜异位症进行肠切除后的长期结果,在疼痛和复发率方面良好,妊娠率为50%。

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