Mwape Kabemba E, Phiri Isaac K, Praet Nicolas, Dorny Pierre, Muma John B, Zulu Gideon, Speybroeck Niko, Gabriël Sarah
Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia; Department of Veterinary Tropical Diseases, Faculty of Veterinary Sciences, University of Pretoria, Pretoria, South Africa; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium; Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; Department of Disease Control, School of Veterinary Medicine, University of Zambia, Zambia; Petauke District Hospital, Petauke, Zambia; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium.
Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia; Department of Veterinary Tropical Diseases, Faculty of Veterinary Sciences, University of Pretoria, Pretoria, South Africa; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium; Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; Department of Disease Control, School of Veterinary Medicine, University of Zambia, Zambia; Petauke District Hospital, Petauke, Zambia; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
Am J Trop Med Hyg. 2015 Jan;92(1):56-63. doi: 10.4269/ajtmh.13-0593. Epub 2014 Nov 17.
Taenia solium taeniasis/cysticercosis is an important public health problem occurring mainly in developing countries. This work aimed to study the determinants of human T. solium infections in the Eastern province of Zambia and rank them in order of importance. A household (HH)-level questionnaire was administered to 680 HHs from 53 villages in two rural districts and the taeniasis and cysticercosis status determined. A classification tree model (CART) was used to define the relative importance and interactions between different predictor variables in their effect on taeniasis and cysticercosis. The Katete study area had a significantly higher taeniasis and cysticercosis prevalence than the Petauke area. The CART analysis for Katete showed that the most important determinant for cysticercosis infections was the number of HH inhabitants (6 to 10) and for taeniasis was the number of HH inhabitants > 6. The most important determinant in Petauke for cysticercosis was the age of head of household > 32 years and for taeniasis it was age < 55 years. The CART analysis showed that the most important determinant for both taeniasis and cysticercosis infections was the number of HH inhabitants (6 to 10) in Katete district and age in Petauke. The results suggest that control measures should target HHs with a high number of inhabitants and older individuals.
猪带绦虫病/囊尾蚴病是一个主要发生在发展中国家的重要公共卫生问题。这项研究旨在探讨赞比亚东部省份人类感染猪带绦虫的决定因素，并按重要性进行排序。对两个农村地区53个村庄的680户家庭进行了家庭层面问卷调查，并确定了猪带绦虫病和囊尾蚴病的患病情况。采用分类树模型（CART）来确定不同预测变量对猪带绦虫病和囊尾蚴病影响的相对重要性及相互作用。卡特特研究地区的猪带绦虫病和囊尾蚴病患病率显著高于佩陶凯地区。卡特特地区的CART分析表明，囊尾蚴病感染的最重要决定因素是家庭居民数量（6至10人），而猪带绦虫病的最重要决定因素是家庭居民数量>6人。佩陶凯地区囊尾蚴病的最重要决定因素是户主年龄>32岁，猪带绦虫病的最重要决定因素是年龄<55岁。CART分析表明，卡特特地区猪带绦虫病和囊尾蚴病感染的最重要决定因素是家庭居民数量（6至10人），而在佩陶凯地区则是年龄。结果表明，控制措施应针对居民数量多的家庭和老年人。
