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老年髋部骨折手术时机与死亡率:一项回顾性多中心队列研究。

The timing of surgery and mortality in elderly hip fractures: A retrospective, multicenteric cohort study.

作者信息

Choi Hyuk Joong, Kim Euichung, Shin Young Jeon, Choi Bo Youl, Kim Young Ho, Lim Tae Ho

机构信息

Department of Emergency Medicine, College of Medicine, Hanyang University, Seoul, South Korea.

Departments of Emergency Medicine, CHA University, Gyeonggi-do, South Korea.

出版信息

Indian J Orthop. 2014 Nov;48(6):599-604. doi: 10.4103/0019-5413.144232.

Abstract

BACKGROUND

Early surgery is recommended for elderly hip fracture patients, but some studies show no clear advantage. The benefits of early surgery may differ according to the medical environment in different countries. The purpose of this study was to identify the potential benefits of early surgery in elderly hip fracture patients by evaluating the effect of timing of surgery on mortality.

MATERIALS AND METHODS

A retrospective study was conducted at multiple centers on hip fracture patients aged over 65 years. The primary outcome was 1 year mortality and the secondary outcomes were 30-day/6-month mortality and complications during admission. The effect of time to surgery on mortality was analyzed using a Cox proportional-hazards model.

RESULTS

Among the 874 patients, 162 (18.5%) received surgery within 3 days and their 1-year mortality rate was 9.9%. However, the 1-year mortality rate for the delayed surgery group was 12.5%. After adjustment for potential confounders, the 1-year mortality rates in patients who received surgery in 3-7 days (Hazard ratio = 1.0; 95% confidence interval [CI]: 0.7-1.6) and over 7 days (hazard ratio = 1.3; 95% CI: 0.9-1.8) were not significantly different. In addition, the time to surgery did not have a significant effect on 30-day mortality, 60-day mortality or complications arising during hospitalization.

CONCLUSIONS

The time to surgery did not affect short and long term mortality or the in hospital complication rate in elderly hip fracture patients. We recommend concentrating more on optimizing the condition of patients early with sufficient medical treatment rather than being bound by absolute timing of surgery.

摘要

背景

对于老年髋部骨折患者,推荐早期手术,但一些研究显示并无明显优势。早期手术的益处可能因不同国家的医疗环境而异。本研究的目的是通过评估手术时机对死亡率的影响,确定早期手术在老年髋部骨折患者中的潜在益处。

材料与方法

在多个中心对65岁以上的髋部骨折患者进行了一项回顾性研究。主要结局是1年死亡率,次要结局是30天/6个月死亡率以及住院期间的并发症。使用Cox比例风险模型分析手术时间对死亡率的影响。

结果

在874例患者中,162例(18.5%)在3天内接受了手术,其1年死亡率为9.9%。然而,延迟手术组的1年死亡率为12.5%。在对潜在混杂因素进行调整后,在3 - 7天接受手术的患者(风险比 = 1.0;95%置信区间[CI]:0.7 - 1.6)和超过7天接受手术的患者(风险比 = 1.3;95%CI:0.9 - 1.8)的1年死亡率无显著差异。此外,手术时间对30天死亡率、60天死亡率或住院期间出现的并发症没有显著影响。

结论

手术时间并未影响老年髋部骨折患者的短期和长期死亡率或住院并发症发生率。我们建议更多地关注早期充分医疗治疗以优化患者状况,而非受绝对手术时机的限制。

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