Ojo Omorogieva, Brooke Joanne
Faculty of Education and Health, University of Greenwich, Avery Hill Road, Avery Hill Campus, London, SE9 2UG, UK.
Nutrients. 2014 Nov 18;6(11):5142-52. doi: 10.3390/nu6115142.
The aim of this systematic review is to evaluate the role of enteral nutrition in managing patients with diabetes on enteral feed. The prevalence of diabetes is on the increase in the UK and globally partly due to lack of physical activities, poor dietary regimes and genetic susceptibility. The development of diabetes often leads to complications such as stroke, which may require enteral nutritional support. The provision of enteral feeds comes with its complications including hyperglycaemia which if not managed can have profound consequences for the patients in terms of clinical outcomes. Therefore, it is essential to develop strategies for managing patients with diabetes on enteral feed with respect to the type and composition of the feed. This is a systematic review of published peer reviewed articles. EBSCOhost Research, PubMed and SwetsWise databases were searched. Reference lists of identified articles were reviewed. Randomised controlled trials comparing enteral nutrition diabetes specific formulas with standard formulas were included. The studies which compared diabetes specific formulas (DSF) with standard formulas showed that DSF was more effective in controlling glucose profiles including postprandial glucose, HbA1c and insulinemic response. The use of DSF appears to be effective in managing patients with diabetes on enteral feed compared with standard feed.
本系统评价的目的是评估肠内营养在管理接受肠内喂养的糖尿病患者中的作用。在英国及全球范围内，糖尿病的患病率都在上升，部分原因是缺乏体育活动、不良的饮食习惯和遗传易感性。糖尿病的发展常常导致中风等并发症，而这些并发症可能需要肠内营养支持。提供肠内喂养会带来包括高血糖在内的并发症，如果不加以管理，就临床结局而言，可能会给患者带来严重后果。因此，针对接受肠内喂养的糖尿病患者，制定关于喂养类型和成分的管理策略至关重要。这是一项对已发表的同行评审文章的系统评价。检索了EBSCOhost Research、PubMed和SwetsWise数据库。对已识别文章的参考文献列表进行了审查。纳入了比较肠内营养糖尿病专用配方与标准配方的随机对照试验。将糖尿病专用配方（DSF）与标准配方进行比较的研究表明，DSF在控制血糖指标（包括餐后血糖、糖化血红蛋白和胰岛素反应）方面更有效。与标准喂养相比，使用DSF似乎对管理接受肠内喂养的糖尿病患者有效。
