Yasa Bilal, Arslan Hakan, Akcay Merve, Kavrik Fevzi, Hatirli Huseyin, Ozkan Bulent
Department of Restorative Dentistry, Faculty of Dentistry, Izmir Katip Celebi University, Izmir, Turkey.
Clin Oral Investig. 2015 Jul;19(6):1437-42. doi: 10.1007/s00784-014-1364-5. Epub 2014 Nov 22.
To investigate the whitening effects of different bleaching agents on teeth discoloured by different antibiotic combinations of ciprofloxacin and metronidazole with minocycline, doxycycline, amoxicillin or cefaclor.
Forty extracted bovine incisors were collected and discoloured with triple antibiotic pastes (TAP) with minocycline, doxycycline, amoxicillin and cefaclor throughout 30 days. The specimens were then randomly divided into two subgroups and each group received different bleaching materials: 35% hydrogen peroxide and sodium perborate. Spectrophotometric measurements were obtained on the buccal surfaces of the crown, firstly in the beginning, then on the 4th, 8th and 12th days after the placement of the bleaching materials. The acceptability threshold was set to 3.5. The ∆E values were calculated and the data was analysed using the repeated measures analysis of variance (P = .05).
All the test groups induced colour changes exceeding the acceptability threshold 30 days after the antibiotic pastes were placed. The 35% hydrogen peroxide was more effective than sodium perborate in the whitening of discoloured teeth by antibiotic pastes (P = .001). The whitening effect after the 8th and 12th days was significantly more than after 4 days of treatment (P <.001). The discolouration caused by the TAP with minocycline and cefaclor showed greater whitening compared to the TAP with doxycycline and amoxicillin groups (P <.05).
The whitening treatment effect of 35% hydrogen peroxide on teeth discoloured by antibiotic pastes seems to have significantly outperformed the sodium perborate treatment. Both bleaching agents were allowed to bleach the teeth gradually each day and the effects on the 8th and 12th days were superior to the one on the 4th day.
The use of 35% hydrogen peroxide could be advantageous to bleach the teeth discoloured with antibiotic pastes compared to sodium perborate.
研究不同漂白剂对因环丙沙星与甲硝唑分别联合米诺环素、多西环素、阿莫西林或头孢克洛导致牙齿变色的美白效果。
收集40颗拔除的牛切牙，用含米诺环素、多西环素、阿莫西林和头孢克洛的三联抗生素糊剂（TAP）使其变色30天。然后将标本随机分为两个亚组，每组接受不同的漂白材料：35%过氧化氢和过硼酸钠。在牙冠颊面进行分光光度测量，首先在开始时测量，然后在放置漂白材料后的第4、8和12天测量。可接受阈值设定为3.5。计算∆E值，并使用重复测量方差分析（P = 0.05）分析数据。
放置抗生素糊剂30天后，所有测试组均导致颜色变化超过可接受阈值。在漂白因抗生素糊剂变色的牙齿方面，35%过氧化氢比过硼酸钠更有效（P = 0.001）。第8天和第12天后的美白效果明显优于治疗4天后（P < 0.001）。与含多西环素和阿莫西林的TAP组相比，含米诺环素和头孢克洛的TAP组引起的变色显示出更大的美白效果（P < 0.05）。
35%过氧化氢对因抗生素糊剂变色牙齿的美白治疗效果似乎明显优于过硼酸钠治疗。两种漂白剂均使牙齿每天逐渐变白，第8天和第12天的效果优于第4天。
与过硼酸钠相比，使用35%过氧化氢漂白因抗生素糊剂变色的牙齿可能更具优势。
