Lattari Eduardo, Pereira-Junior Pedro Paulo, Neto Geraldo Albuquerque Maranhão, Lamego Murilo Khede, Moura Antonio Marcos de Souza, de Sá Alberto Souza, Rimes Ridson Rosa, Manochio João Paulo, Arias-Carrión Oscar, Mura Gioia, Nardi Antonio E, Machado Sergio
Panic & Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute for Translational Medicine (INCT-TM), Brazil.
Physical Activity Neuroscience, Physical Activity Postgraduate Program, Salgado de Oliveira University (UNIVERSO), Niterói - RJ, Brazil;
Clin Pract Epidemiol Ment Health. 2014 Nov 14;10:126-8. doi: 10.2174/1745017901410010126. eCollection 2014.
Exercise produces potential influences on physical and mental capacity in patients with neuropsychiatric disorders, and can be made a viable form of therapy to treat Parkinson's disease (PD). We report the chronic effects of a regular physical exercise protocol on cognitive and motor functions, functional capacity, and symptoms in an elderly PD patient without dementia. The patient participated of a program composed of proprioceptive, aerobic and flexibility exercises, during 1 hour, three days a week, for nine months. Patient used 600 mg of L-DOPA daily, and 1 hour prior to each exercise session. Assessment was conducted in three stages, 0-3, 3-6 and 6 to 9 months, using percentual variation to the scales Hoehn and Yahr, Mini-Mental State Examination (MMSE), Parkinson Activity Scale (PAS), Beck Depression Inventory (BDI), and Unified Parkinson's Disease Rating Scale (UPDRS-III). Reassessment showed clear changes in clinical parameters for Hoehn and Yahr (4 to 2.5), MMSE (14 to 22), PAS (13 to 29), BDI (9 to 7) and UPDRS-III (39 to 27) at the end of 9 months. According to our data, exercise seems to be effective in promoting the functional capacity and the maintenance of cognitive and motor functions of PD patients. Regular exercise protocols can be implemented as an adjunctive treatment for reducing the severity of PD.
运动对神经精神疾病患者的身心能力产生潜在影响,并且可以成为治疗帕金森病(PD)的一种可行治疗方式。我们报告了一项常规体育锻炼方案对一名无痴呆的老年PD患者的认知和运动功能、功能能力及症状的长期影响。该患者参加了一个由本体感觉、有氧运动和柔韧性练习组成的项目,每周三天,每次1小时,持续九个月。患者每天服用600毫克左旋多巴,且在每次锻炼前1小时服用。在三个阶段进行评估,即0至3个月、3至6个月和6至9个月,使用Hoehn和Yahr量表、简易精神状态检查表(MMSE)、帕金森活动量表(PAS)、贝克抑郁量表(BDI)和统一帕金森病评定量表(UPDRS-III)的百分比变化。重新评估显示,在9个月末,Hoehn和Yahr量表(从4到2.5)、MMSE(从14到22)、PAS(从13到29)、BDI(从9到7)和UPDRS-III(从39到27)的临床参数有明显变化。根据我们的数据,运动似乎对促进PD患者的功能能力以及维持其认知和运动功能有效。常规锻炼方案可以作为辅助治疗来减轻PD的严重程度。