Represa A, Le Gall La Salle G, Ben-Ari Y
INSERM U29, Paris, France.
Neurosci Lett. 1989 May 8;99(3):345-50. doi: 10.1016/0304-3940(89)90471-0.
Histochemical and autoradiographic techniques were used to study mossy fiber sprouting which occurs in the hippocampus of kindled rats. In rats kindled by daily stimulation of amygdala or entorhinal cortex, the mossy fibers sprout to innervate the supragranular zone of fascia dentata; this synaptic reorganization was associated with a significant increase in the density of high-affinity kainic acid binding sites. Amygdala but not entorhinal kindling also induces sprouting of mossy fibers in the stratum infrapyramidale of CA3.
采用组织化学和放射自显影技术研究点燃大鼠海马中发生的苔藓纤维发芽。在通过每日刺激杏仁核或内嗅皮质而点燃的大鼠中，苔藓纤维发芽并支配齿状回颗粒上层；这种突触重组与高亲和力 kainic 酸结合位点密度的显著增加有关。杏仁核点燃而非内嗅皮质点燃也诱导 CA3 锥体下区的苔藓纤维发芽。
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