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Aberrant growth of mossy fibers and enhanced kainic acid binding sites induced in rats by early hyperthyroidism.

作者信息

Represa A, Tremblay E, Ben-Ari Y

机构信息

INSERM U29, Laboratoire de Neurobiologie et Physiopathologie du Développement, Paris, France.

出版信息

Brain Res. 1987 Oct 13;423(1-2):325-8. doi: 10.1016/0006-8993(87)90856-0.

DOI:10.1016/0006-8993(87)90856-0
PMID:2823988
Abstract

Early hyperthyroidism induces an aberrant growth of hippocampal mossy fibers both in the fascia dentata (supragranular layer) and in Ammon's horn (infrapyramidal layer of CA3). Using a quantitative autoradiographic method, we found a corresponding increase in kainic acid binding sites supporting previous observations of a very close association between mossy fiber terminals and kainic acid binding sites.

摘要

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