Marcotorchino Julie, Tourniaire Franck, Landrier Jean-François
INRA, UMR 1260, F-13385 Marseille, France.
Horm Mol Biol Clin Investig. 2013 Sep;15(3):123-8. doi: 10.1515/hmbci-2013-0027.
Epidemiological studies have shown a link between vitamin D deficiency and numerous pathologies such as cancers, immunity diseases, cardiovascular diseases, hypertension, type 2 diabetes, and obesity. Recent studies in vitro and in animal models demonstrated an impact of vitamin D on adipose tissue and adipocyte biology. Such observations are of particular interest and provide mechanistic explanations on the relationship between vitamin D deficiency and obesity.
流行病学研究表明，维生素D缺乏与多种疾病之间存在联系，如癌症、免疫疾病、心血管疾病、高血压、2型糖尿病和肥胖症。最近在体外和动物模型中的研究表明，维生素D对脂肪组织和脂肪细胞生物学有影响。这些观察结果特别令人感兴趣，并为维生素D缺乏与肥胖之间的关系提供了机制上的解释。
