College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, Henan 453003, China.
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Can J Gastroenterol Hepatol. 2020 Feb 18;2020:2656321. doi: 10.1155/2020/2656321. eCollection 2020.
Vitamin D has been discovered centuries ago, and current studies have focused on the biological effects of vitamin D on adipogenesis. Besides its role in calcium homeostasis and energy metabolism, vitamin D is also involved in the regulation of development and process of metabolic disorders. Adipose tissue is a major storage depot of vitamin D. This review summarized studies on the relationship between vitamin D and adipogenesis and furthermore focuses on adipose metabolic disorders. We reviewed the biological roles and functionalities of vitamin D, the correlation between vitamin D and adipose tissue, the effect of vitamin D on adipogenesis, and adipose metabolic diseases. Vitamin D is associated with adipogenesis, and vitamin D supplements can reduce the burden caused by metabolic diseases. The review provides new insights and basis for medical therapy on adipose metabolic diseases.
维生素 D 的发现可以追溯到几个世纪以前，目前的研究主要集中在维生素 D 对脂肪生成的生物学作用上。除了在钙稳态和能量代谢中的作用外，维生素 D 还参与了代谢紊乱的发育和过程的调节。脂肪组织是维生素 D 的主要储存库。本综述总结了维生素 D 与脂肪生成之间的关系，并进一步关注了脂肪代谢紊乱。我们回顾了维生素 D 的生物学作用和功能、维生素 D 与脂肪组织的相关性、维生素 D 对脂肪生成的影响以及脂肪代谢疾病。维生素 D 与脂肪生成有关，维生素 D 补充剂可以减轻代谢疾病带来的负担。该综述为脂肪代谢疾病的医学治疗提供了新的见解和依据。
Zotero 插件