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接受化疗或放疗患者的生育力保存

Fertility preservation in patients receiving chemotherapy or radiotherapy.

作者信息

Robinson Randal D, Knudtson Jennifer F

出版信息

Mo Med. 2014 Sep-Oct;111(5):434-8.

PMID:25438367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6172082/
Abstract

The preservation and restoration of fertility are key aspects for enhancing quality of life in cancer survivors. Cytotoxic agents and radiation can produce gonadal dysfunction in both men and women. Survival rates for cancers that occur before or during reproductive age have improved dramatically. Current fertility preservation options are available but limited in males and females. Referral to a reproductive endocrinologist around the time of diagnosis is important to optimize treatment options.

摘要

生育能力的保存和恢复是提高癌症幸存者生活质量的关键方面。细胞毒性药物和辐射可导致男性和女性的性腺功能障碍。发生在生殖年龄之前或期间的癌症患者生存率已显著提高。目前有一些生育力保存方法可供选择,但在男性和女性中都很有限。在诊断时转诊至生殖内分泌专家对于优化治疗方案很重要。

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Fertility preservation in patients receiving chemotherapy or radiotherapy.接受化疗或放疗患者的生育力保存
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本文引用的文献

1
Fertility preservation and reproduction in patients facing gonadotoxic therapies: a committee opinion.面临性腺毒性治疗的患者的生育力保存和生殖:委员会意见。
Fertil Steril. 2013 Nov;100(5):1224-31. doi: 10.1016/j.fertnstert.2013.08.041. Epub 2013 Oct 2.
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Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion.行性腺毒性治疗或性腺切除术患者的生育力保存:委员会意见。
Fertil Steril. 2013 Nov;100(5):1214-23. doi: 10.1016/j.fertnstert.2013.08.012. Epub 2013 Sep 5.
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J Clin Oncol. 2013 Jul 1;31(19):2500-10. doi: 10.1200/JCO.2013.49.2678. Epub 2013 May 28.
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Obstet Gynecol. 2013 Jan;121(1):78-86. doi: 10.1097/aog.0b013e31827374e2.
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Fertility preservation in women of reproductive age with cancer.癌症患者生育力保存的相关问题
Am J Obstet Gynecol. 2012 Dec;207(6):455-62. doi: 10.1016/j.ajog.2012.08.013. Epub 2012 Aug 10.
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Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer.促性腺激素释放激素激动剂曲普瑞林用于乳腺癌新辅助化疗中卵巢功能保护的随机试验。
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Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy induced premature ovarian failure in premenopausal women.辅助性促性腺激素释放激素类似物用于预防绝经前女性化疗引起的卵巢早衰
Cochrane Database Syst Rev. 2011 Nov 9(11):CD008018. doi: 10.1002/14651858.CD008018.pub2.
8
Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.促性腺激素释放激素类似物曲普瑞林对乳腺癌绝经前妇女化疗诱导早绝经发生的影响:一项随机试验。
JAMA. 2011 Jul 20;306(3):269-76. doi: 10.1001/jama.2011.991.
9
Effect of luteinizing hormone-releasing hormone agonist on ovarian function after modern adjuvant breast cancer chemotherapy: the GBG 37 ZORO study.黄体生成素释放激素激动剂对现代辅助乳腺癌化疗后卵巢功能的影响:GBG 37 ZORO 研究。
J Clin Oncol. 2011 Jun 10;29(17):2334-41. doi: 10.1200/JCO.2010.32.5704. Epub 2011 May 2.
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Gonadotropin-releasing hormone analog cotreatment for preservation of ovarian function during gonadotoxic chemotherapy: a systematic review and meta-analysis.促性腺激素释放激素类似物联合治疗在性腺毒性化疗中保护卵巢功能的系统评价和荟萃分析。
Fertil Steril. 2011 Mar 1;95(3):906-14.e1-4. doi: 10.1016/j.fertnstert.2010.11.017. Epub 2010 Dec 10.