Center of Innovation in Long-Term Services and Supports, Providence Veterans Affairs Medical Center, Providence, RI; Department of Medicine, Alpert Medical School of Brown University, Providence, RI; Medical Service, Providence Veterans Affairs, Providence, RI.
Center of Innovation in Long-Term Services and Supports, Providence Veterans Affairs Medical Center, Providence, RI.
Am Heart J. 2014 Nov;168(5):713-20. doi: 10.1016/j.ahj.2014.06.024. Epub 2014 Jul 11.
The few available studies of the Centers for Medicare and Medicaid Services Hospital Inpatient Quality Reporting (IQR) care process indicators have not linked receipt of recommended care processes in heart failure (HF) with lower mortality. Because the Veterans Health Administration (VHA) also tracks hospital inpatient quality reporting indicators, in addition to VHA-specific inpatient (pneumococcal and influenza vaccination) and outpatient (angiotensin-converting enzyme inhibitor [ACEI] or angiotensin receptor blocker [ARB] use for left ventricular [LV] dysfunction and LV function documentation) care process indicators, we examined the association between receipt of these care processes and 30-day and 1-year mortality.
Retrospective study of 107,045 patients with HF treated at 128 VHA hospitals between 2001 and 2007 and followed up through 2008. We assessed the relationship between receipt of each HF care process and death at 30 days (inpatients only) and 1 year (all patients), using generalized estimating equations to adjust for clinical characteristics and clustering within hospitals.
Overall, inpatient/outpatient use of ACEI/ARB and receipt of pneumococcal or influenza vaccinations were related to lower risks of 30-day and/or 1-year mortality (adjusted odds ratios 0.51-0.77 for vaccinations and 0.60-0.78 for ACEI/ARB use). Conversely, discharge instructions, inpatient/outpatient LV function assessment, or weight instructions before admission were either not related or related to a slightly increase in mortality. Stratified analyses by various mortality risk subgroups did not reveal discernable "dose-response" relationship between mortality risk stratification and the association of care process and mortality.
Receipt of care processes related to recommended medications and vaccinations were associated with lower 30-day and/or 1-year risk-adjusted mortality in patients with HF. Receipt of care processes that assess patient counseling or chart documentation was not related to lower mortality.
为数不多的关于医疗保险和医疗补助服务中心(Centers for Medicare and Medicaid Services)医院住院患者质量报告(IQR)护理过程指标的研究表明,接受推荐的心力衰竭(HF)护理过程并不能降低死亡率。由于退伍军人健康管理局(Veterans Health Administration)除了跟踪医院住院患者质量报告指标外,还跟踪住院患者(肺炎球菌和流感疫苗接种)和门诊患者(左心室功能障碍和左心室功能文档的血管紧张素转换酶抑制剂[ACEI]或血管紧张素受体阻滞剂[ARB]使用)护理过程指标,我们研究了接受这些护理过程与 30 天和 1 年死亡率之间的关系。
对 2001 年至 2007 年期间在 128 家退伍军人健康管理局医院接受治疗并随访至 2008 年的 107045 例 HF 患者进行回顾性研究。我们使用广义估计方程来调整临床特征和医院内的聚类,评估每个 HF 护理过程的接受情况与 30 天(仅住院患者)和 1 年(所有患者)死亡之间的关系。
总体而言,门诊/住院使用 ACEI/ARB 和接种肺炎球菌或流感疫苗与降低 30 天和/或 1 年死亡率的风险相关(调整后的比值比为 0.51-0.77 用于疫苗接种和 0.60-0.78 用于 ACEI/ARB 使用)。相反,入院前的出院指导、门诊/住院左心室功能评估或体重指导与死亡率的增加无关或相关。根据各种死亡率风险亚组进行的分层分析并未发现死亡率风险分层与护理过程和死亡率之间的关联存在明显的“剂量-反应”关系。
接受与推荐药物和疫苗接种相关的护理过程与 HF 患者的 30 天和/或 1 年风险调整后死亡率降低相关。接受评估患者咨询或图表文档的护理过程与死亡率降低无关。