Shikov Alexander N, Pozharitskaya Olga N, Makarov Valery G, Yang Wen-Zhi, Guo De-An
Saint-Petersburg Institute of Pharmacy, 188663, Kuzmolovo P 245, Russia.
Saint-Petersburg Institute of Pharmacy, 188663, Kuzmolovo P 245, Russia.
Chin J Nat Med. 2014 Oct;12(10):721-9. doi: 10.1016/S1875-5364(14)60111-4. Epub 2014 Oct 31.
Oplopanax elatus (Nakai) Nakai, a member of the ancient angiosperm plant family Araliaceae, is used for the treatment of different disorders in the medicine systems of China, Russia, and Korea, and was designated in Russia as a classical adaptogen. Despite extensive studies of classical adaptogens, there are comparatively few reports concerning the chemical composition and pharmacological effects of O. elatus in English. The plant is a potential source of saponins, flavonoids, anthraquinones, terpenes, and other active compounds. Experimental studies and clinical applications have indicated that O. elatus possesses a number of pharmacological activities, including adaptogenic, anti-convulsant, anti-diabetic, anti-fungal, anti-inflammatory, anti-oxidant, blood pressure modulating, and reproductive function effects. In this review, the chemistry, safety, and therapeutic potential of O. elatus are summarized and highlighted to encourage the further development of this plant.
辽东楤木（Oplopanax elatus (Nakai) Nakai）是古老被子植物五加科的一员，在中国、俄罗斯和韩国的医学体系中用于治疗各种疾病，在俄罗斯被指定为经典适应原。尽管对经典适应原进行了广泛研究，但关于辽东楤木化学成分和药理作用的英文报道相对较少。该植物是皂苷、黄酮类化合物、蒽醌、萜类和其他活性化合物的潜在来源。实验研究和临床应用表明，辽东楤木具有多种药理活性，包括适应原、抗惊厥、抗糖尿病、抗真菌、抗炎、抗氧化、血压调节和生殖功能作用。在本综述中，总结并强调了辽东楤木的化学、安全性和治疗潜力，以促进该植物的进一步开发。
