School of Environmental Science and Engineering, Gwangju Institute of Science and Technology, Republic of Korea.
Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do 446-701, Republic of Korea.
Bioresour Technol. 2015 Feb;177:361-74. doi: 10.1016/j.biortech.2014.11.022. Epub 2014 Nov 15.
Microbial conversion of syngas to energy-dense biofuels and valuable chemicals is a potential technology for the efficient utilization of fossils (e.g., coal) and renewable resources (e.g., lignocellulosic biomass) in an environmentally friendly manner. However, gas-liquid mass transfer and kinetic limitations are still major constraints that limit the widespread adoption and successful commercialization of the technology. This review paper provides rationales for syngas bioconversion and summarizes the reaction limited conditions along with the possible strategies to overcome these challenges. Mass transfer and economic performances of various reactor configurations are compared, and an ideal case for optimum bioreactor operation is presented. Overall, the challenges with the bioprocessing steps are highlighted, and potential solutions are suggested. Future research directions are provided and a conceptual design for a membrane-based syngas biorefinery is proposed.
将合成气转化为高能量密度生物燃料和有价值的化学品是一种以环保的方式有效利用化石（如煤）和可再生资源（如木质纤维素生物质）的潜在技术。然而，气液传质和动力学限制仍然是限制该技术广泛应用和成功商业化的主要制约因素。本文综述了合成气生物转化的合理性，并总结了反应受限条件以及克服这些挑战的可能策略。比较了各种反应器构型的传质和经济性能，并提出了一种理想的最佳生物反应器操作案例。总体而言，本文强调了生物加工步骤所面临的挑战，并提出了潜在的解决方案。提供了未来的研究方向，并提出了基于膜的合成气生物炼制厂的概念设计。
