Institute of Biochemical Engineering, University of Stuttgart, Allmandring 31, 70569, Stuttgart, Germany.
BASF SE, Bio-Process Development, Carl-Bosch-Str. 38, 67056, Ludwigshafen, Germany.
Microb Biotechnol. 2018 Jul;11(4):606-625. doi: 10.1111/1751-7915.13270. Epub 2018 May 14.
The reduction of CO emissions is a global effort which is not only supported by the society and politicians but also by the industry. Chemical producers worldwide follow the strategic goal to reduce CO emissions by replacing existing fossil-based production routes with sustainable alternatives. The smart use of CO and CO /H mixtures even allows to produce important chemical building blocks consuming the said gases as substrates in carboxydotrophic fermentations with acetogenic bacteria. However, existing industrial infrastructure and market demands impose constraints on microbes, bioprocesses and products that require careful consideration to ensure technical and economic success. The mini review provides scientific and industrial facets finally to enable the successful implementation of gas fermentation technologies in the industrial scale.
减少 CO 排放是一项全球性的努力，不仅得到了社会和政治家的支持，也得到了工业界的支持。全球的化学生产商都遵循着通过用可持续的替代品替代现有基于化石的生产路线来减少 CO 排放的战略目标。明智地利用 CO 和 CO/H 混合物甚至可以使重要的化学基础结构单元的生产成为可能，即将上述气体作为乙酰基形成细菌的羧基营养发酵的基质进行消耗。然而，现有的工业基础设施和市场需求对需要仔细考虑的微生物、生物工艺和产品施加了限制，以确保技术和经济上的成功。该小型综述提供了科学和工业方面的内容，最终使气体发酵技术能够在工业规模上成功实施。
