Reynolds Mary Ann, McCully Kevin, Burdett Blake, Manella Christine, Hawkins Laura, Backus Deborah
Department of Kinesiology, University of Georgia, Athens, GA.
Department of Kinesiology, University of Georgia, Athens, GA.
Arch Phys Med Rehabil. 2015 Apr;96(4):627-32. doi: 10.1016/j.apmr.2014.10.010. Epub 2014 Nov 4.
To investigate the changes in muscle oxygen consumption (mV˙O2) using near-infrared spectroscopy (NIRS) after 4 weeks of training with functional electrical stimulation (FES) cycling in nonambulatory people with multiple sclerosis (MS).
Four-week before-after trial to assess changes in mV˙O2 after an FES cycling intervention.
Rehabilitation hospital.
People (N=8; 7 men, 1 women) from a volunteer/referred sample with moderate to severe MS (Expanded Disability Status Scale score>6.0).
Participants cycled 30 minutes per session, 3d/wk for 4 weeks or a total of 12 sessions.
mV˙O2 of the right vastus lateralis muscle was measured with NIRS before and within 1 week after the intervention. Six bouts of 15-second electrical stimulation increasing from 2 to 7Hz were used to activate the muscle. mV˙O2 was assessed by analyzing the slope of the NIRS oxygen signal during a 10-second arterial occlusion after each electrical stimulation bout.
Significant FES training by electrical stimulation frequency level interaction was observed (P=.031), with an average increase in mV˙O2 of 47% across frequencies with a main effect of training (P=.047).
FES cycling for 4 weeks improved mV˙O2, suggesting that FES cycling is a potential therapy for improving muscle health in people with MS who are nonambulatory.
采用近红外光谱技术（NIRS），研究非行走型多发性硬化症（MS）患者在接受功能性电刺激（FES）骑行训练4周后肌肉耗氧量（mV˙O2）的变化情况。
进行为期4周的前后对照试验，以评估FES骑行干预后mV˙O2的变化。
康复医院。
来自志愿者/转诊样本的8名患者（7名男性，1名女性），患有中度至重度MS（扩展残疾状态量表评分>6.0）。
参与者每次骑行30分钟，每周3次，共4周，总计12次训练。
在干预前及干预后1周内，使用NIRS测量右侧股外侧肌的mV˙O2。通过6组每次持续15秒、频率从2Hz增加到7Hz的电刺激来激活肌肉。在每次电刺激后，通过分析10秒动脉闭塞期间NIRS氧信号的斜率来评估mV˙O2。
观察到电刺激频率水平交互作用对FES训练有显著影响（P = 0.031），各频率下mV˙O2平均增加47%，训练有主要效应（P = 0.047）。
4周的FES骑行训练可改善mV˙O2，表明FES骑行是改善非行走型MS患者肌肉健康状况的一种潜在治疗方法。
