Haug Elisabeth, Øie Merete, Andreassen Ole A, Bratlien Unni, Nelson Barnaby, Aas Monica, Møller Paul, Melle Ingrid
Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway.
Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway; Department of Psychology, University of Oslo, Oslo, Norway.
Compr Psychiatry. 2015 Jan;56:35-41. doi: 10.1016/j.comppsych.2014.10.005. Epub 2014 Oct 16.
Anomalous self-experiences (ASEs) are viewed as core features of schizophrenia. Childhood trauma (CT) has been postulated as a risk factor for developing schizophrenia.
The aim of this study is to investigate the relationships between CT, depression and ASEs in schizophrenia.
ASEs were assessed in 55 patients in the early treated phases of schizophrenia using the Examination of Anomalous Self-Experience (EASE) instrument. Data on CT were collected using the Childhood Trauma Questionnaire, short form (CTQ-SF). This consists of 5 subscales: physical abuse, sexual abuse, emotional abuse, emotional neglect, and physical neglect. Assessment of depression was based on the Calgary Depression Scale for Schizophrenia (CDSS).
We found significant associations between EASE total score and CTQ total score and between EASE total score and emotional neglect subscore in women, but not men. We also found significant associations between CDSS total score and CTQ total score and between CDSS total score and emotional abuse, emotional neglect, and physical neglect subscores in women, but not men. In men we did not find any significant associations between EASE total score, CDSS total score and any CTQ scores.
CT was significantly associated with higher levels of ASEs in women in the early treated phases of schizophrenia, but not in men. This again associated with an increase in depressive symptoms.
异常自我体验（ASEs）被视为精神分裂症的核心特征。童年创伤（CT）被假定为精神分裂症发病的一个危险因素。
本研究旨在探讨精神分裂症中童年创伤、抑郁与异常自我体验之间的关系。
使用异常自我体验检查表（EASE）对55例处于精神分裂症早期治疗阶段的患者进行异常自我体验评估。使用儿童创伤问卷简版（CTQ-SF）收集童年创伤数据。该问卷由5个分量表组成：躯体虐待、性虐待、情感虐待、情感忽视和躯体忽视。基于卡尔加里精神分裂症抑郁量表（CDSS）对抑郁进行评估。
我们发现，女性的EASE总分与CTQ总分之间以及EASE总分与情感忽视分量表得分之间存在显著关联，而男性不存在。我们还发现，女性的CDSS总分与CTQ总分之间以及CDSS总分与情感虐待、情感忽视和躯体忽视分量表得分之间存在显著关联，而男性不存在。在男性中，我们未发现EASE总分、CDSS总分与任何CTQ得分之间存在任何显著关联。
在精神分裂症早期治疗阶段，童年创伤与女性较高水平的异常自我体验显著相关，但与男性无关。这也与抑郁症状的增加有关。
