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Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.

作者信息

Petri Marcelo H, Laguna-Fernandez Andrés, Tseng Chi-Nan, Hedin Ulf, Perretti Mauro, Bäck Magnus

机构信息

Translational Cardiology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Vascular Surgery, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

出版信息

Int J Cardiol. 2015 Jan 20;179:370-2. doi: 10.1016/j.ijcard.2014.11.010. Epub 2014 Nov 5.

DOI:10.1016/j.ijcard.2014.11.010
PMID:25464488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4274317/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2583/4274317/d421e4fddce6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2583/4274317/4a1c5205066d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2583/4274317/d421e4fddce6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2583/4274317/4a1c5205066d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2583/4274317/d421e4fddce6/gr2.jpg

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Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.阿司匹林触发的15-表-脂氧素A₄通过血管平滑肌细胞中的FPR2/ALX发出信号,并在颈动脉结扎后预防内膜增生。
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2
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本文引用的文献

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The role of the FPR2/ALX receptor in atherosclerosis development and plaque stability.FPR2/ALX受体在动脉粥样硬化发展和斑块稳定性中的作用。
Cardiovasc Res. 2015 Jan 1;105(1):65-74. doi: 10.1093/cvr/cvu224. Epub 2014 Oct 23.
2
Pro-resolving lipid mediators are leads for resolution physiology.促炎消退脂质介质是解决生理学的研究线索。
Nature. 2014 Jun 5;510(7503):92-101. doi: 10.1038/nature13479.
3
Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7.白三烯、脂氧素和氧代二十碳烯酸受体的最新进展:IUPHAR综述7
组织因子靶向肽增强纳米颗粒与合成的特殊促消退脂质介质的结合,并将其递送至受损动脉。
JVS Vasc Sci. 2023 Sep 26;4:100126. doi: 10.1016/j.jvssci.2023.100126. eCollection 2023.
4
Biomimetic Nanocarriers of Pro-Resolving Lipid Mediators for Resolution of Inflammation in Atherosclerosis.用于解决动脉粥样硬化炎症的促消退脂质介质的仿生纳米载体
Adv Healthc Mater. 2024 Jan;13(3):e2302238. doi: 10.1002/adhm.202302238. Epub 2023 Nov 8.
5
Critical Role of Inflammation and Specialized Pro-Resolving Mediators in the Pathogenesis of Atherosclerosis.炎症和特殊促消退介质在动脉粥样硬化发病机制中的关键作用
Biomedicines. 2022 Nov 6;10(11):2829. doi: 10.3390/biomedicines10112829.
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Mesenchymal Stem Cells and Formyl Peptide Receptor 2 Activity in Hyperoxia-Induced Lung Injury in Newborn Mice.骨髓间充质干细胞和甲酰肽受体 2 活性在新生小鼠高氧诱导肺损伤中的作用。
Int J Mol Sci. 2022 Sep 13;23(18):10604. doi: 10.3390/ijms231810604.
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Biochem Biophys Res Commun. 2013 Nov 15;441(2):393-8. doi: 10.1016/j.bbrc.2013.10.078. Epub 2013 Oct 23.
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FASEB J. 2013 Jun;27(6):2220-32. doi: 10.1096/fj.12-225615. Epub 2013 Feb 13.
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Sci Transl Med. 2011 Oct 5;3(103):103ra98. doi: 10.1126/scitranslmed.3002531.
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Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis.阿司匹林触发的脂氧素和解析素 E1 调节血管平滑肌表型,并与周围动脉粥样硬化相关。
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Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):518-24. doi: 10.1161/ATVBAHA.108.181750. Epub 2009 Jan 22.
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