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1
Sequence of the coding regions from the 3.0 kb and 3.9 kb mRNA. Subgenomic species from a virulent isolate of transmissible gastroenteritis virus.来自3.0 kb和3.9 kb mRNA的编码区序列。来自传染性胃肠炎病毒强毒株的亚基因组种类。
Arch Virol. 1989;105(3-4):165-78. doi: 10.1007/BF01311354.
2
The integral membrane protein from a virulent isolate of transmissible gastroenteritis virus: molecular characterization, sequence and expression in Escherichia coli.传染性胃肠炎病毒强毒株的整合膜蛋白：分子特征、序列及在大肠杆菌中的表达
Mol Microbiol. 1988 Jul;2(4):497-505. doi: 10.1111/j.1365-2958.1988.tb00056.x.
3
Sequence of the S gene from a virulent British field isolate of transmissible gastroenteritis virus.来自英国一株传染性胃肠炎病毒强毒株的S基因序列。
Virus Res. 1990 Dec;18(1):71-80. doi: 10.1016/0168-1702(90)90090-x.
4
Genetic basis for the pathogenesis of transmissible gastroenteritis virus.传染性胃肠炎病毒发病机制的遗传基础。
J Virol. 1990 Oct;64(10):4761-6. doi: 10.1128/JVI.64.10.4761-4766.1990.
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Sequence comparison of the 5' end of mRNA 3 from transmissible gastroenteritis virus and porcine respiratory coronavirus.传染性胃肠炎病毒和猪呼吸道冠状病毒mRNA 3 5'端的序列比较
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Nucleotide sequence of coronavirus TGEV genomic RNA: evidence for 3 mRNA species between the peplomer and matrix protein genes.冠状病毒猪传染性胃肠炎病毒基因组RNA的核苷酸序列：在纤突蛋白和基质蛋白基因之间存在三种mRNA的证据。
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Sequence of the nucleoprotein gene from a virulent British field isolate of transmissible gastroenteritis virus and its expression in Saccharomyces cerevisiae.来自一株英国强毒力传染性胃肠炎病毒田间分离株的核蛋白基因序列及其在酿酒酵母中的表达。
Mol Microbiol. 1988 Jan;2(1):89-99.
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Enteric coronavirus TGEV: partial sequence of the genomic RNA, its organization and expression.肠道冠状病毒猪传染性胃肠炎病毒：基因组RNA的部分序列、其结构与表达
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Cloning and sequencing of a 8.4-kb region from the 3'-end of a Taiwanese virulent isolate of the coronavirus transmissible gastroenteritis virus.对台湾地区传染性胃肠炎病毒强毒株3'-末端一个8.4 kb区域进行克隆和测序。
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The cloning and sequencing of the virion protein genes from a British isolate of porcine respiratory coronavirus: comparison with transmissible gastroenteritis virus genes.一株英国猪呼吸道冠状病毒分离株病毒粒子蛋白基因的克隆与测序：与传染性胃肠炎病毒基因的比较
Virus Res. 1991 Nov;21(3):181-98. doi: 10.1016/0168-1702(91)90032-q.

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Virology. 2000 Mar 30;269(1):172-82. doi: 10.1006/viro.2000.0218.
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The major product of porcine transmissible gastroenteritis coronavirus gene 3b is an integral membrane glycoprotein of 31 kDa.猪传染性胃肠炎冠状病毒基因3b的主要产物是一种31 kDa的整合膜糖蛋白。
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Nucleotide sequence of the inter-structural gene region of feline infectious peritonitis virus.猫传染性腹膜炎病毒结构间基因区域的核苷酸序列。
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Sequence comparison of porcine respiratory coronavirus isolates reveals heterogeneity in the S, 3, and 3-1 genes.猪呼吸道冠状病毒分离株的序列比较揭示了S、3和3-1基因的异质性。
J Virol. 1995 May;69(5):3176-84. doi: 10.1128/JVI.69.5.3176-3184.1995.
5
Genetic basis for the pathogenesis of transmissible gastroenteritis virus.传染性胃肠炎病毒发病机制的遗传基础。
J Virol. 1990 Oct;64(10):4761-6. doi: 10.1128/JVI.64.10.4761-4766.1990.
6
Sequence of the S gene from a virulent British field isolate of transmissible gastroenteritis virus.来自英国一株传染性胃肠炎病毒强毒株的S基因序列。
Virus Res. 1990 Dec;18(1):71-80. doi: 10.1016/0168-1702(90)90090-x.
7
Sequence analysis of the leader RNA of two porcine coronaviruses: transmissible gastroenteritis virus and porcine respiratory coronavirus.两种猪冠状病毒（传染性胃肠炎病毒和猪呼吸道冠状病毒）前导RNA的序列分析
Virus Genes. 1990 Dec;4(4):289-301. doi: 10.1007/BF00570024.
8
Genetic analysis of porcine respiratory coronavirus, an attenuated variant of transmissible gastroenteritis virus.猪呼吸道冠状病毒的遗传分析，一种传染性胃肠炎病毒的减毒变体。
J Virol. 1991 Jun;65(6):3369-73. doi: 10.1128/JVI.65.6.3369-3373.1991.
9
The cloning and sequencing of the virion protein genes from a British isolate of porcine respiratory coronavirus: comparison with transmissible gastroenteritis virus genes.一株英国猪呼吸道冠状病毒分离株病毒粒子蛋白基因的克隆与测序：与传染性胃肠炎病毒基因的比较
Virus Res. 1991 Nov;21(3):181-98. doi: 10.1016/0168-1702(91)90032-q.
10
Sequence analysis of human coronavirus 229E mRNAs 4 and 5: evidence for polymorphism and homology with myelin basic protein.人冠状病毒229E mRNA 4和5的序列分析：多态性及与髓鞘碱性蛋白同源性的证据
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本文引用的文献

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Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.原核生物、真核生物和细胞器中蛋白质合成起始的比较。
Microbiol Rev. 1983 Mar;47(1):1-45. doi: 10.1128/mr.47.1.1-45.1983.
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Location and direction of transcription of the ptsH and ptsI genes on the Escherichia coli K12 genome.大肠杆菌K12基因组上ptsH和ptsI基因的转录位置及方向
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Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus.小鼠肝炎病毒（一种细胞质RNA病毒）病毒粒子和信使核糖核酸上前导RNA序列的特征分析
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Cotranslational and posttranslational processing of viral glycoproteins.病毒糖蛋白的共翻译和翻译后加工。
Curr Top Microbiol Immunol. 1980;90:19-48. doi: 10.1007/978-3-642-67717-5_2.
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Coronavirus mRNA synthesis involves fusion of non-contiguous sequences.冠状病毒信使核糖核酸的合成涉及不连续序列的融合。
EMBO J. 1983;2(10):1839-44. doi: 10.1002/j.1460-2075.1983.tb01667.x.
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Los Alamos sequence analysis package for nucleic acids and proteins.洛斯阿拉莫斯核酸与蛋白质序列分析软件包。
Nucleic Acids Res. 1982 Jan 11;10(1):183-96. doi: 10.1093/nar/10.1.183.
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Sequencing of coronavirus IBV genomic RNA: a 195-base open reading frame encoded by mRNA B.冠状病毒传染性支气管炎病毒（IBV）基因组RNA测序：由mRNA B编码的一个195个碱基的开放阅读框。
Gene. 1984 Jul-Aug;29(1-2):87-92. doi: 10.1016/0378-1119(84)90169-0.
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A leader sequence is present on mRNA A of avian infectious bronchitis virus.禽传染性支气管炎病毒的mRNA A上存在一个前导序列。
J Gen Virol. 1984 Aug;65 ( Pt 8):1437-42. doi: 10.1099/0022-1317-65-8-1437.
9
Antibody responses in serum, colostrum, and milk of swine after infection or vaccination with transmissible gastroenteritis virus.猪感染或接种传染性胃肠炎病毒后血清、初乳和乳汁中的抗体反应。
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Coding sequence of coronavirus MHV-JHM mRNA 4.冠状病毒MHV-JHM mRNA 4的编码序列。
J Gen Virol. 1985 Mar;66 ( Pt 3):593-6. doi: 10.1099/0022-1317-66-3-593.

来自3.0 kb和3.9 kb mRNA的编码区序列。来自传染性胃肠炎病毒强毒株的亚基因组种类。

Sequence of the coding regions from the 3.0 kb and 3.9 kb mRNA. Subgenomic species from a virulent isolate of transmissible gastroenteritis virus.

作者信息

Britton P, Lopez Otin C, Martin Alonso J, Parra F

机构信息

Division of Microbiology, A.F.R.C. Institute for Animal Health, Compton Laboratory, Newbury, Berks, U.K.

出版信息

Arch Virol. 1989;105(3-4):165-78. doi: 10.1007/BF01311354.

DOI:10.1007/BF01311354
PMID:2546515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7086989/
Abstract

Subgenomic mRNA from a virulent isolate of porcine transmissible gastroenteritis virus (TGEV) was used to produce cDNA clones covering the genome region from the 3' end of the peplomer gene to the start of the integral membrane protein gene. The nucleotide sequence of this area was determined using clone pTG11 and a previously reported cDNA clone pTG22. Three open reading frames (ORFs) were identified encoding putative polypeptides of relative molecular masses (Mr) 6,600, 27,600, and 9,200. The sequence encoding the Mr 9,200 polypeptide was found to be present on the "unique" 5' region of the 3.0 kb mRNA species whereas the other two ORFs mapped on the 3.9 kb mRNA species. Differences between the ORFs from this strain of TGEV and those from a previously reported avirulent strain of TGEV were compared.

摘要

来自猪传染性胃肠炎病毒（TGEV）强毒株的亚基因组mRNA被用于制备覆盖从纤突蛋白基因3'末端到整合膜蛋白基因起始处的基因组区域的cDNA克隆。使用克隆pTG11和先前报道的cDNA克隆pTG22测定了该区域的核苷酸序列。鉴定出三个开放阅读框（ORF），它们编码相对分子质量（Mr）分别为6,600、27,600和9,200的推定多肽。发现编码Mr 9,200多肽的序列存在于3.0 kb mRNA种类的“独特”5'区域，而其他两个ORF定位在3.9 kb mRNA种类上。比较了该TGEV毒株的ORF与先前报道的TGEV无毒株的ORF之间的差异。