冠状病毒信使核糖核酸的合成涉及不连续序列的融合。
Coronavirus mRNA synthesis involves fusion of non-contiguous sequences.
作者信息
Spaan W, Delius H, Skinner M, Armstrong J, Rottier P, Smeekens S, van der Zeijst B A, Siddell S G
出版信息
EMBO J. 1983;2(10):1839-44. doi: 10.1002/j.1460-2075.1983.tb01667.x.
Abstract
Positive-stranded genomic RNA of coronavirus MHV and its six subgenomic mRNAs are synthesized in the cytoplasm of the host cell. The mRNAs are composed of leader and body sequences which are non-contiguous on the genome and are fused together in the cytoplasm by a mechanism which appears to involve an unusual and specific 'polymerase jumping' event.
摘要
冠状病毒MHV的正链基因组RNA及其六种亚基因组mRNA在宿主细胞的细胞质中合成。这些mRNA由前导序列和主体序列组成，它们在基因组上不连续，并通过一种似乎涉及异常且特定的“聚合酶跳跃”事件的机制在细胞质中融合在一起。
Zotero 插件