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多重耐药铜绿假单胞菌菌株CCBH4851的基因组序列草图,该菌株是一株医院分离株,属于在巴西流行的克隆SP(ST277)。

The draft genome sequence of multidrug-resistant Pseudomonas aeruginosa strain CCBH4851, a nosocomial isolate belonging to clone SP (ST277) that is prevalent in Brazil.

作者信息

Silveira Melise, Albano Rodolpho, Asensi Marise, Assef Ana Paula Carvalho

机构信息

Laboratório de Pesquisa em Infecção Hospitalar, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brasil.

Departamento de Bioquímica, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2014 Dec;109(8):1086-7. doi: 10.1590/0074-0276140336. Epub 2014 Dec 2.

Abstract

The high occurrence of nosocomial multidrug-resistant (MDR) microorganisms is considered a global health problem. Here, we report the draft genome sequence of a MDR Pseudomonas aeruginosa strain isolated in Brazil that belongs to the endemic clone ST277. The genome encodes important resistance determinant genes and consists of 6.7 Mb with a G+C content of 66.86% and 6,347 predicted coding regions including 60 RNAs.

摘要

医院内多重耐药(MDR)微生物的高发生率被认为是一个全球健康问题。在此,我们报告了一株在巴西分离出的属于地方流行克隆ST277的多重耐药铜绿假单胞菌菌株的基因组序列草图。该基因组编码重要的耐药决定基因,由6.7 Mb组成,G+C含量为66.86%,预测有6347个编码区,包括60个RNA。

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