Department of Chemistry and ‡Department of Physics, Imperial College London , South Kensington Campus, London, SW7 2AZ, United Kingdom.
Nano Lett. 2015 Jan 14;15(1):553-9. doi: 10.1021/nl504536j. Epub 2014 Dec 8.
Targeted temperature control in nanopores is greatly important in further understanding biological molecules. Such control would extend the range of examinable molecules and facilitate advanced analysis, including the characterization of temperature-dependent molecule conformations. The work presented within details well-defined plasmonic gold bullseye and silicon nitride nanopore membranes. The bullseye nanoantennae are designed and optimized using simulations and theoretical calculations for interaction with 632.8 nm laser light. Laser heating was monitored experimentally through nanopore conductance measurements. The precise heating of nanopores is demonstrated while minimizing the accumulation of heat in the surrounding membrane material.
在纳米孔中进行靶向温度控制对于进一步了解生物分子非常重要。这种控制将扩大可检测分子的范围，并促进高级分析，包括温度依赖性分子构象的表征。本文详细介绍了定义明确的等离子体金靶心和氮化硅纳米孔膜。使用模拟和理论计算设计和优化了靶心纳米天线，以与 632.8nm 激光相互作用。通过纳米孔电导测量实验监测激光加热。在最小化周围膜材料中热量积累的同时，实现了纳米孔的精确加热。
