Shirai Toshihiro, Mochizuki Eisuke, Asada Kazuhiro, Suda Takafumi
Department of Respiratory Medicine, Shizuoka General Hospital Shizuoka, Japan.
Second Department of Internal Medicine, Hamamatsu University School of Medicine Hamamatsu, Japan.
Respirol Case Rep. 2014 Sep;2(3):113-5. doi: 10.1002/rcr2.68. Epub 2014 Aug 19.
The subject was a 52-year-old man with Japanese cedar pollinosis, which developed between February and May. He had no history of asthma and was an ex-smoker. He underwent fractional exhaled nitric oxide (FeNO) measurements twice a week from 2010 to 2012. The pollen counts in 2010 were the lowest during the last decade, and the FeNO level was less than 30 ppb for the whole year. In contrast, the mean pollen count in 2011 was very high and the patient's FeNO level rose to more than 100 ppb. The mean pollen count in 2012 was comparable with that of 2010; however, high counts were detected in April and May, and the FeNO level rose to 70 ppb during the latter stages of the pollen season. These results indicate that pollen counts should be taken into consideration during the interpretation of FeNO data in asthma or allergic rhinitis.
该患者为一名52岁男性,患有日本雪松花粉症,发病时间为2月至5月。他没有哮喘病史,且已戒烟。从2010年到2012年,他每周进行两次呼出一氧化氮分数(FeNO)测量。2010年的花粉计数是过去十年中最低的,全年FeNO水平低于30 ppb。相比之下,2011年的平均花粉计数非常高,患者的FeNO水平升至100 ppb以上。2012年的平均花粉计数与2010年相当;然而,4月和5月检测到高计数,花粉季节后期FeNO水平升至70 ppb。这些结果表明,在解释哮喘或过敏性鼻炎的FeNO数据时应考虑花粉计数。