Hu Xue-Bin, Feng Zhe, Fan Yu-Cong, Xiong Zhi-Yong, Huang Qi-Wei
Department of Neurosurgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China.
Brain Inj. 2012;26(2):183-7. doi: 10.3109/02699052.2011.648707.
To assess health-related quality-of-life (HRQoL) 2 years after traumatic brain injury (TBI) among a group of Chinese.
A total of 358 adult patients with moderate-to-severe TBI based on Glasgow Coma Scale score were recruited in a large trauma centre in Wuhan, China during May 2005 to April 2008. They were followed up for 2 years and the Medical Outcome Short Form 36 was used to measure HRQoL.
After a 2-year follow-up, there were 312 (87.2%) survivors. All domains of HRQoL had the lowest scores at discharge, greatly improved over the first 6 months and showed continued improvement. Patients with TBI still had significantly lower scores in every domain than the reference group 2 years after discharge. Female patients had lower MCS scores than the males (OR = 1.8, 95% CI: 1.1-2.9). Patients older than 30 had lower scores in PCS (OR = 1.7, 95% CI: 1.1-2.6). Patients with severe TBI had lower scores in both PCS (OR = 1.9, 95% CI: 1.2-3.1) and MCS (OR = 1.6, 95% CI: 1.0-2.6) compared with those with moderate TBI.
HRQoL of a group of Chinese patients with TBI improved during 2 years after discharge. Age, sex and severity of TBI were significantly associated with physical or mental HRQoL after discharge.
评估一组中国人创伤性脑损伤（TBI）2年后的健康相关生活质量（HRQoL）。
2005年5月至2008年4月期间，在中国武汉的一家大型创伤中心招募了358例基于格拉斯哥昏迷量表评分的中重度TBI成年患者。对他们进行了2年的随访，并使用医学结局简明量表36来测量HRQoL。
经过2年的随访，有312例（87.2%）幸存者。HRQoL的所有领域在出院时得分最低，在最初6个月内大幅改善，并持续改善。TBI患者出院2年后在每个领域的得分仍显著低于参照组。女性患者的MCS得分低于男性（OR = 1.8，95%CI：1.1 - 2.9）。30岁以上的患者PCS得分较低（OR = 1.7，95%CI：1.1 - 2.6）。与中度TBI患者相比，重度TBI患者的PCS（OR = 1.9，95%CI：1.2 - 3.1）和MCS（OR = 1.6，95%CI：1.0 - 2.6）得分均较低。
一组中国TBI患者的HRQoL在出院后2年内有所改善。TBI的年龄、性别和严重程度与出院后的身体或心理HRQoL显著相关。
