Shimizu Takayuki, Ishizuka Mitsuru, Kubota Keiichi
Second Department of Surgery, Dokkyo Medical University, 880 Kitakobayashi, Tochigi, Mibu, 321-0293, Japan.
Surg Today. 2015 Nov;45(11):1404-10. doi: 10.1007/s00595-014-1086-y. Epub 2014 Dec 6.
Although surgical site infections (SSI) are a major postoperative complication of appendectomy, few studies have focused on the risk factors for SSI. In this study, we investigated the risk factors for SSI in patients who had undergone appendectomy.
Three hundred patients who had undergone open appendectomy were enrolled. The patients were divided into two groups based on the presence or absence of SSI. A statistical analysis was performed to assess the clinical features associated with SSI after appendectomy.
A multivariate analysis using the results of univariate analyses revealed that the serum C-reactive protein (CRP) level (≤ 65/> 65, mg/l), length of the operation (≤ 80/> 80, min) and pathology (catarrhal, phlegmonous/gangrenous) were associated with SSI. Among these three clinical features, only the CRP level was found to predict the risk of SSI prior to appendectomy (odds ratio 3.797; 95 % confidence intervals 1.305-11.04; P = 0.014).
Preoperative elevation of the serum CRP level (> 65 mg/l) is a valuable predictor of SSI in patients undergoing appendectomy.
尽管手术部位感染（SSI）是阑尾切除术后的主要并发症，但很少有研究关注SSI的危险因素。在本研究中，我们调查了接受阑尾切除术患者发生SSI的危险因素。
纳入300例行开放性阑尾切除术的患者。根据是否发生SSI将患者分为两组。进行统计分析以评估阑尾切除术后与SSI相关的临床特征。
多变量分析显示，血清C反应蛋白（CRP）水平（≤65/>65，mg/l）、手术时间（≤80/>80，分钟）和病理类型（卡他性、蜂窝织炎性/坏疽性）与SSI相关。在这三个临床特征中，只有CRP水平被发现可在阑尾切除术前预测SSI风险（比值比3.797；95%置信区间1.305 - 11.04；P = 0.014）。
术前血清CRP水平升高（>65 mg/l）是阑尾切除术后患者发生SSI的重要预测指标。
