Oliva Francesco, Osti Leonardo, Padulo Johnny, Maffulli Nicola
Department of Orthopaedic and Traumatology, University of Rome "Tor Vergata", School of Medicine, Rome, Italy.
Unit of Arthroscopic and Sports Medicine, Hesperia Hospital, Modena, Italy.
Muscles Ligaments Tendons J. 2014 Nov 17;4(3):309-14. eCollection 2014 Jul.
in the last years the incidence of rotator cuff tears increased and one main cause still waiting to be clarified. Receptors for thyroid hormones in rotator cuff tendons suggest possible effects on tendons metabolism and status. We undertook a retrospective, observational cohort study of 441 patients who underwent arthroscopic and mini-open repair for non traumatic degenerative rotator cuff tears.
all the patients, predominantly females (63%), were interview to assess the relationship (frequency for class age "20 yrs" and factor analysis) between lesions of the rotator cuff with the following variables: gender, thyroid disease, smoker, taking medications for diabetes, hypertension or high cholesterol; presence of associated conditions (diabetes, hypertension, hypercholesterolemia).
thyroid disease is highly frequently (until 63% for 60<80 yrs) in females group independent to the age. Conversely, males showed a high frequency for smoker 37<62% until 80 yrs and 50% hypercholesterolemia over 80 yrs for the clinical variable studied.
this is the first clinical report that shown a relationship between thyroid pathologies and non-traumatic rotator cuff tear as increased risk factors.
近年来,肩袖撕裂的发病率有所上升,一个主要原因仍有待阐明。肩袖肌腱中的甲状腺激素受体提示其可能对肌腱代谢和状态产生影响。我们对441例因非创伤性退行性肩袖撕裂接受关节镜和小切口开放修复手术的患者进行了一项回顾性观察队列研究。
所有患者中女性占主导(63%),对其进行访谈以评估肩袖损伤与以下变量之间的关系(年龄分组“20岁”的频率及因素分析):性别、甲状腺疾病、吸烟者、服用治疗糖尿病、高血压或高胆固醇的药物情况;是否存在相关疾病(糖尿病、高血压、高胆固醇血症)。
在女性组中,甲状腺疾病的发生率很高(60至80岁年龄段高达63%),且与年龄无关。相反,在所研究的临床变量中,男性吸烟者的比例较高(37至62%,直至80岁),80岁以上高胆固醇血症的比例为50%。
这是第一份临床报告,表明甲状腺疾病与非创伤性肩袖撕裂之间存在关联,且为风险增加因素。