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目标线索对阿尔茨海默病与帕金森病痴呆患者日常行动错误的不同影响。

Differential effects of goal cues on everyday action errors in Alzheimer's disease versus Parkinson's disease dementia.

作者信息

Giovannetti Tania, Seligman Sarah C, Britnell Priscilla, Brennan Laura, Libon David J

机构信息

Department of Psychology, Temple University.

Department of Neurology, Drexel University College of Medicine.

出版信息

Neuropsychology. 2015 Jul;29(4):592-602. doi: 10.1037/neu0000167. Epub 2014 Dec 15.

Abstract

OBJECTIVE

Prior research has shown that individuals with Parkinson's disease dementia (PDD) show a different pattern of error types on everyday tasks compared with individuals with Alzheimer's disease (AD). This study evaluated whether these groups would respond differently to cues designed to remind participants of task goals and improve performance of everyday tasks (i.e., goal cues).

METHOD

Participants with PDD (n = 20) and AD (n = 20), and a comparison group of individuals with Parkinson's disease and no dementia (n = 20), were administered performance-based tasks of everyday functioning that allowed for the quantification of errors before and after the presentation of goal cues.

RESULTS

AD participants showed a significantly greater response to the goal cues as compared with individuals with PDD. The goal cues facilitated the completion of task goals but did not promote error correction (i.e., the undoing of errors that had been made earlier during the task).

CONCLUSIONS

Not all dementia patients respond similarly to cues designed to improve everyday functioning. Understanding patients' specific form of everyday action impairment is crucial for developing individualized interventions that target specific functional deficits.

摘要

目的

先前的研究表明,与患有阿尔茨海默病(AD)的个体相比,患有帕金森病痴呆(PDD)的个体在日常任务中表现出不同的错误类型模式。本研究评估了这些组对旨在提醒参与者任务目标并改善日常任务表现的提示(即目标提示)的反应是否会有所不同。

方法

对患有PDD的参与者(n = 20)、患有AD的参与者(n = 20)以及一组无痴呆的帕金森病个体组成的对照组(n = 20)进行基于表现的日常功能任务测试,以便在呈现目标提示之前和之后对错误进行量化。

结果

与患有PDD的个体相比,患有AD的参与者对目标提示的反应明显更大。目标提示促进了任务目标的完成,但并未促进错误纠正(即在任务早期已经出现的错误的纠正)。

结论

并非所有痴呆患者对旨在改善日常功能的提示都有相似的反应。了解患者日常行动障碍的具体形式对于制定针对特定功能缺陷的个性化干预措施至关重要。

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