State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, People's Republic of China.
Nanoscale. 2015 Jan 28;7(4):1296-300. doi: 10.1039/c4nr04889j.
Protein-DNA interactions are known to play an important role in a variety of biological processes. We have shown here that protein-DNA binding events can also be used to greatly improve the fluorescence stability of DNA-templated Ag nanoclusters (Ag NCs), which would be highly beneficial for Ag NCs in applications of biosensing/imaging.
蛋白质与 DNA 的相互作用在多种生物过程中起着重要作用。我们在这里表明,蛋白质与 DNA 的结合事件也可用于极大地提高 DNA 模板化 Ag 纳米团簇(Ag NCs)的荧光稳定性,这将对 Ag NCs 在生物传感/成像应用中非常有益。