神经性厌食症儿童及青少年的认知概况
Cognitive profile of children and adolescents with anorexia nervosa.
作者信息
Kjaersdam Telléus Gry, Jepsen Jens Richardt, Bentz Mette, Christiansen Eva, Jensen Signe O W, Fagerlund Birgitte, Thomsen Per Hove
机构信息
Unit for Psychiatric Research, Aalborg University Hospital, Aalborg, Denmark; Section of Eating Disorders, Unit for Child and Adolescent Psychiatry, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
出版信息
Eur Eat Disord Rev. 2015 Jan;23(1):34-42. doi: 10.1002/erv.2337. Epub 2014 Dec 11.
OBJECTIVE
Few studies of cognitive functioning in children and adolescents with anorexia nervosa (AN) have been conducted. The aim of this study was to examine the neurocognitive and intelligence profile of this clinical group.
METHOD
The study was a matched case-control (N = 188), multi-centre study including children and adolescents with AN (N = 94) and healthy control participants (N = 94).
RESULTS
The results suggest that Full Scale Intelligence Quotient (Wechsler Intelligence Scale for Children-III/Wechsler Adult Intelligence Scale-III) in this patient group is close to the normal population mean of 100. Individuals with AN exhibited significantly worse performance in nonverbal intelligence functions (i.e. Wechsler Intelligence Scale for Children-III/Wechsler Adult Intelligence Scale-III, Perceptual Organization Index) and in verbal memory (Test of Memory and Learning-Second Edition, Memory for Stories) and motor speed (Cambridge Neuropsychological Test Automated Battery, Simple and Choice Reaction Time) compared with healthy control participants. No significant difference in set-shifting ability (Cambridge Neuropsychological Test Automated Battery, Intra-Extra Dimensional Set Shift and Trail Making Test B) was found.
CONCLUSIONS
Inefficiency in nonverbal intelligence functions and in specific cognitive functions was found in this study of children and adolescents with AN.
目的
针对神经性厌食症（AN）儿童及青少年的认知功能，此前开展的研究较少。本研究旨在探究该临床群体的神经认知及智力特征。
方法
本研究为一项匹配病例对照研究（N = 188），多中心研究，纳入了患有AN的儿童及青少年（N = 94）以及健康对照参与者（N = 94）。
结果
结果表明，该患者群体的全量表智商（韦氏儿童智力量表第三版/韦氏成人智力量表第三版）接近正常人群均值100。与健康对照参与者相比，患有AN的个体在非言语智力功能（即韦氏儿童智力量表第三版/韦氏成人智力量表第三版，知觉组织指数）、言语记忆（记忆与学习测试第二版，故事记忆）及运动速度（剑桥神经心理测试自动成套系统，简单反应时和选择反应时）方面表现明显更差。在转换能力方面（剑桥神经心理测试自动成套系统，维度内-维度间转换及连线测验B）未发现显著差异。
结论
在本项针对患有AN的儿童及青少年的研究中，发现其非言语智力功能及特定认知功能存在低效情况。
Zotero 插件