Suppr超能文献

预测社交恐惧症认知疗法结局和脱落率的基线患者特征:一项大型多中心试验的结果

Baseline Patient Characteristics Predicting Outcome and Attrition in Cognitive Therapy for Social Phobia: Results from a Large Multicentre Trial.

作者信息

Hoyer Juergen, Wiltink Joerg, Hiller Wolfgang, Miller Robert, Salzer Simone, Sarnowsky Stephan, Stangier Ulrich, Strauss Bernhard, Willutzki Ulrike, Leibing Eric

机构信息

Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.

出版信息

Clin Psychol Psychother. 2016 Jan-Feb;23(1):35-46. doi: 10.1002/cpp.1936. Epub 2014 Dec 11.

Abstract

UNLABELLED

We examined the role of baseline patient characteristics as predictors of outcome (end-state functioning, response and remission) and attrition for cognitive therapy (CT) in social anxiety disorder (SAD). Beyond socio-demographic and clinical variables such as symptom severity and comorbidity status, previously neglected patient characteristics (e.g., personality, self-esteem, shame, interpersonal problems and attachment style) were analysed.

METHOD

Data came from the CT arm of a multicentre RCT with n = 244 patients having DSM-IV SAD. CT was conducted according to the manual by Clark and Wells. Severity of SAD was assessed at baseline and end of treatment with the Liebowitz Social Anxiety Scale (LSAS). Multiple linear regression analyses and logistic regression analyses were applied.

RESULTS

Up to 37% of the post-treatment variance (LSAS) could be explained by all pre-treatment variables combined. Symptom severity (baseline LSAS) was consistently negatively associated with end-state functioning and remission, but not with response. Number of comorbid diagnoses was negatively associated with end-state functioning and response, but not with remission. Self-esteem was positively associated with higher end-state functioning and more shame with better response. Attrition could not be significantly predicted.

CONCLUSIONS

The results indicate that the initial probability for treatment success mainly depends on severity of disorder and comorbid conditions while other psychological variables are of minor importance, at least on a nomothetic level. This stands in contrast with efforts to arrive at an empirical-based foundation for differential indication and argues to search for more potent moderators of therapeutic change rather on the process level.

KEY PRACTITIONER MESSAGE

Personality, self-esteem, shame, attachment style and interpersonal problems do not or only marginally moderate the effects of interventions in CT of social phobia. Symptom severity and comorbid diagnoses might affect treatment outcome negatively. Beyond these two factors, most patients share a similar likelihood of treatment success when treated according to the manual by Clark and Wells. Copyright © 2014 John Wiley & Sons, Ltd.

摘要

未标注

我们研究了基线患者特征作为社交焦虑障碍(SAD)认知疗法(CT)结局(最终状态功能、反应和缓解)及治疗中断预测因素的作用。除了社会人口学和临床变量,如症状严重程度和共病状态外,还分析了先前被忽视的患者特征(如人格、自尊、羞耻感、人际问题和依恋风格)。

方法

数据来自一项多中心随机对照试验的CT组,有244例符合DSM-IV标准的SAD患者。CT按照Clark和Wells的手册进行。使用Liebowitz社交焦虑量表(LSAS)在基线和治疗结束时评估SAD的严重程度。应用多元线性回归分析和逻辑回归分析。

结果

所有治疗前变量综合起来可解释高达37%的治疗后方差(LSAS)。症状严重程度(基线LSAS)始终与最终状态功能和缓解呈负相关,但与反应无关。共病诊断数量与最终状态功能和反应呈负相关,但与缓解无关。自尊与更高的最终状态功能呈正相关,羞耻感越强反应越好。无法显著预测治疗中断情况。

结论

结果表明,治疗成功的初始概率主要取决于疾病严重程度和共病情况,而其他心理变量的重要性较小,至少在一般水平上如此。这与为实现基于实证的差异适应症基础所做的努力形成对比,并主张在过程层面寻找更有效的治疗变化调节因素。

关键从业者信息

人格、自尊、羞耻感、依恋风格和人际问题对社交恐惧症CT干预效果没有或仅有轻微调节作用。症状严重程度和共病诊断可能对治疗结局产生负面影响。除这两个因素外,大多数患者按照Clark和Wells的手册进行治疗时,治疗成功的可能性相似。版权所有© 2014 John Wiley & Sons, Ltd.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验